ID A0A1G4WU15_9MYCO Unreviewed; 320 AA.
AC A0A1G4WU15;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
GN ORFNames=SAMN02799620_04802 {ECO:0000313|EMBL:SCX29516.1};
OS Mycolicibacterium fluoranthenivorans.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=258505 {ECO:0000313|EMBL:SCX29516.1, ECO:0000313|Proteomes:UP000199707};
RN [1] {ECO:0000313|Proteomes:UP000199707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UNC267MFSha1.1M11 {ECO:0000313|Proteomes:UP000199707};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
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DR EMBL; FMUB01000011; SCX29516.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4WU15; -.
DR STRING; 1502745.SAMN02799620_04802; -.
DR Proteomes; UP000199707; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
FT DOMAIN 29..295
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 320 AA; 34448 MW; CDFA568D1D580A3C CRC64;
MRRYPFAFDR AGISVSTMTQ AQVKIPRTAV VPAAGLGTRF LPATKTVPKE LLPVVDTPGI
ELVAAEAAEA GAERLVIITS EGKDGVVAHF VEDLILEGTL EARGKHVMLE KVRRAPALIK
VESVVQAEPL GLGHAVGCVE HKLLPDEDAI AVLLPDDLVL PTGVLETMSK VRAKRGGSVL
CAIEVPEDEI SAYGVFDVEV VPDAANPNVL RVKGMVEKPK AEDAPSLFAA AGRYVLDRAI
FDALRRVDRG VGGEIQLTDA IALLIEEGHP VHVVVHRGSR HDLGNPGGYL KAAVDFALER
DDYGPELRRW LVERLDLVEK
//
