ID   A0A1G4XBA3_9ACTN        Unreviewed;       677 AA.
AC   A0A1G4XBA3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN   Name=flhA {ECO:0000256|RuleBase:RU364093};
GN   ORFNames=SAMN03159343_0412 {ECO:0000313|EMBL:SCX38441.1};
OS   Klenkia marina.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Klenkia.
OX   NCBI_TaxID=1960309 {ECO:0000313|EMBL:SCX38441.1, ECO:0000313|Proteomes:UP000198981};
RN   [1] {ECO:0000313|Proteomes:UP000198981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45722 {ECO:0000313|Proteomes:UP000198981};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC       apparatus. Together with FliI and FliH, may constitute the export
CC       apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC       ECO:0000256|RuleBase:RU364093}.
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DR   EMBL; FMUH01000001; SCX38441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4XBA3; -.
DR   STRING; 1960309.SAMN03159343_0412; -.
DR   OrthoDB; 9759185at2; -.
DR   Proteomes; UP000198981; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR   Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR   Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR006301; FlhA.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   NCBIfam; TIGR01398; FlhA; 1.
DR   PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR   PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW   Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU364093};
KW   Cell projection {ECO:0000313|EMBL:SCX38441.1};
KW   Cilium {ECO:0000313|EMBL:SCX38441.1};
KW   Flagellum {ECO:0000313|EMBL:SCX38441.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW   Protein transport {ECO:0000256|RuleBase:RU364093};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364093};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        30..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        55..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        92..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        188..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        230..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        273..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   REGION          310..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   677 AA;  70896 MW;  53D5EB80F8BAD386 CRC64;
     MKWTTAAVPI GVVAIVLMLV VPMPAMLLDL LIGINIAASL LILLVAMSIK RPLDFAVFPS
     AILIATLLRL ALNVSSTRLV LSDGYAGAVI EAFGHFVIGG SLVVGLVVFL ILVVIQFVVI
     TKGAERVAEV GARFTLDAMP GKQMAIDADL NAGLITEAEA RKRRADVTAE ADFYGSMDGA
     SKFVKGDAIA AIIIVLVNLI GGLIIGMVQG GMSAGDAVST YSLLAVGDGL VSMVPALLLS
     TATGIVVTRS AADGELGQDM IAQLGRRKQP LRIAGGALLA LGLIPGLPKL PFLLTGAIFL
     FLASRVDENP PVEDEAPTPG ADAPSPDSPE AIAEKMRVDP LELEVAFDLV ELVDSARGGD
     LLDRVKALRR KVAMDTGLVI PLVRTRDNLD LPASQYVVWL NGVPVAKGTS PAGTVLAIGD
     SLDGLPGKPT REPVFGLAAK WVPAELQRQA EMAGATVVDR SSVITTHLAE VVRQNAAQLL
     GREDVKLLLE MVRRTHPVVV EELTGGGLSL GQVQQVLQAL LEEGVSIRDL VRIFEAMSLR
     AKTGSDLDSL VEAARGALGP AISHPYVTAD EKLYVMTLDP GFEQRLLSAV RQGEQGAVLA
     LDAGMVDALA RGASDLLDDA EKLGITALLV CSPQVRPALS RLMRQVVARC TVISYAEVSC
     TAQIETIGVV NGAVALA
//