ID A0A1G4XIM8_9ACTN Unreviewed; 390 AA.
AC A0A1G4XIM8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cation diffusion facilitator family transporter {ECO:0000313|EMBL:SCX40528.1};
GN ORFNames=SAMN03159343_0983 {ECO:0000313|EMBL:SCX40528.1};
OS Klenkia marina.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Klenkia.
OX NCBI_TaxID=1960309 {ECO:0000313|EMBL:SCX40528.1, ECO:0000313|Proteomes:UP000198981};
RN [1] {ECO:0000313|Proteomes:UP000198981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45722 {ECO:0000313|Proteomes:UP000198981};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMUH01000001; SCX40528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4XIM8; -.
DR STRING; 1960309.SAMN03159343_0983; -.
DR OrthoDB; 9813655at2; -.
DR Proteomes; UP000198981; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR Gene3D; 3.30.70.1350; Cation efflux protein, cytoplasmic domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027470; Cation_efflux_CTD.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR43840; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR PANTHER; PTHR43840:SF15; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR Pfam; PF16916; ZT_dimer; 1.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 103..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..373
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 41146 MW; 3E455491E115CB2C CRC64;
MTTPSRYNNP DPGRREHTDG HEPRTTSDHG HAAGHGHDTG HGTGTGTGTG TDHGHLEHGH
EHPSGIRGFI LGLIKPHSHD SADSADSALE ASAEGIRALK ISLVVLLLAA LAQAVVVWFT
GSVALLADTV HNFSDALTAV PLWIAFILGR RAASRRYTYG YDRAEDLAGI FIVAMIALSA
VLAGWESVRR LIDPQPITNV GVVITAGLIG AAGNELVALY RIRVGRRIGS AALVADGLHA
RTDGLTSLAV VIGAIGVAAG FPLADPIVGL VITVAILIVL KGAARDVYRR LMDAVEPEVL
DAAETSIRAT PGVLDVERLR VRWTGHRIRA EAAVTVDAQL TVTQGHDIAV DVHHRLLHDV
PELIDATVHV SPAAHGADPH HVLAHHHVPN
//
