ID A0A1G4YVQ0_9BURK Unreviewed; 496 AA.
AC A0A1G4YVQ0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:SCX57476.1};
GN ORFNames=SAMN03159363_1841 {ECO:0000313|EMBL:SCX57476.1};
OS Variovorax sp. EL159.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1566270 {ECO:0000313|EMBL:SCX57476.1, ECO:0000313|Proteomes:UP000199507};
RN [1] {ECO:0000313|EMBL:SCX57476.1, ECO:0000313|Proteomes:UP000199507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EL159 {ECO:0000313|EMBL:SCX57476.1,
RC ECO:0000313|Proteomes:UP000199507};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; FMUJ01000002; SCX57476.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4YVQ0; -.
DR STRING; 1566270.SAMN03159363_1841; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000199507; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 22..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 496 AA; 51645 MW; 8A2D369B7F56DCD7 CRC64;
MTGDTLSSAV HPVDERLPSG KLAALGLQHV LVMYAGAVAV PLIVGRALKL SPDEVALLIS
ADLFCCGIAT LIQALGATQW FGIKLPVMMG VTFASVAPMV AMANANPGQN GAQLLFGSII
GAGVVSIMIA PLVSRMLRFF PPVVTGTIIA VIGISLMRVG INWIFGNPVG PTAPALVDPV
YAKWLAEVTS PGSSIPAVPK GFAIMPTVPN PKYADLSGFG VAALVLVSIL LIVKYAKGFI
ANISVLLGIV IGAVVASLTG LMTYEKVGKA AWVDIVLPFH FGMPQFDPIL ILTMTLIMIV
VMIESTGMFL ALGEMTGRKI DQKDLARGLR TDGLGTLIGG IFNTFPYTSF SQNVGLVAVT
GIKSRYVCVA GGVILMVLGL LPKMAALVES LPTVVLGGAG LVMFGMVAAT GIRILSGVDF
KTNRHNAMIV AVSIGIGMIP LIAPNFKQWM PHAIHSLIES GILLASIAAV LLNLFLNGAK
HDEQAVIAAA KQAEAH
//
