ID   A0A1G5AK09_9PROT        Unreviewed;       692 AA.
AC   A0A1G5AK09;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN   Name=flhA {ECO:0000256|RuleBase:RU364093};
GN   ORFNames=SAMN05216308_101179 {ECO:0000313|EMBL:SCX78248.1};
OS   Nitrosospira sp. Nsp13.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=1855332 {ECO:0000313|EMBL:SCX78248.1, ECO:0000313|Proteomes:UP000198731};
RN   [1] {ECO:0000313|EMBL:SCX78248.1, ECO:0000313|Proteomes:UP000198731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nsp13 {ECO:0000313|EMBL:SCX78248.1,
RC   ECO:0000313|Proteomes:UP000198731};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC       apparatus. Together with FliI and FliH, may constitute the export
CC       apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC       ECO:0000256|RuleBase:RU364093}.
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DR   EMBL; FMVD01000001; SCX78248.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5AK09; -.
DR   OrthoDB; 9759185at2; -.
DR   Proteomes; UP000198731; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR   Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR   Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR006301; FlhA.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   NCBIfam; TIGR01398; FlhA; 1.
DR   PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR   PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW   Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU364093};
KW   Cell projection {ECO:0000313|EMBL:SCX78248.1};
KW   Cilium {ECO:0000313|EMBL:SCX78248.1};
KW   Flagellum {ECO:0000313|EMBL:SCX78248.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW   Protein transport {ECO:0000256|RuleBase:RU364093};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364093};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT   TRANSMEM        21..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        45..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        114..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        206..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        248..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
SQ   SEQUENCE   692 AA;  73968 MW;  78439EA69B6C7120 CRC64;
     MNMIAKFNHI FSGVNARSLT GPLLILMILG MMVLPLPAFV LDMMFTFNIA LSIMVLLVSI
     HTHKPLEFAV FPTVLLLTTL LRLSLNVAST RIVLMEGHTG PDAAGKVIEA FGHYLVGGNY
     AVGIVVFIIL VVINFIVITK GAGRIAEVAA RFTLDAMPGK QMAIDADLNA GLLGEEEAGK
     RRTAIAQEAE FYGSMDGASK FVRGDAIAGI LILFINVIGG LLVGVLQHDL DMATAAKTYT
     LLAIGDGLVA QIPALIISTA AGLVVSRVGT DEDISGQLVS QLFSRPQVLV LTAAIIGLMG
     LIPGMPHIAF LLLAAVLGGG AYMMTQREKR AAGRVAVAPA AQPEVQDASW DDVTPVDVLG
     LEVGYRLISL VDRAQDGELL RRIKGVRKKF AQEIGYLPPS VHIRDNLELR PNAYRITLKG
     VAIGAGEVNV SQYLAINPGG VSGTLPGLAT SDPAFGLPAI WIEASQRDQA QIMGYTVVDP
     GTVVATHLNH LMHTHAAELL GRLEVQQLLD RMAKDSPKLV EDLTPKLLPL STVQKVLQNL
     LDESVHIRDM RTIIDAMAEH AARVQDPHEL TALIRIALGR AIVQQIWPQS GELQVMALDA
     GLERLLTQAL QASPNSAGIE PGLADTLMRE AAGASQRQEQ VGLVPVLLVP APLRTLLARF
     LRRALPQLKI LSHAEVPDSS NIKVTSILGA RA
//