ID A0A1G5AMK8_9FIRM Unreviewed; 719 AA.
AC A0A1G5AMK8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DNA helicase-2 / ATP-dependent DNA helicase PcrA {ECO:0000313|EMBL:SCX79084.1};
GN ORFNames=SAMN02910292_00028 {ECO:0000313|EMBL:SCX79084.1};
OS Lachnospiraceae bacterium XBB2008.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1520826 {ECO:0000313|EMBL:SCX79084.1, ECO:0000313|Proteomes:UP000199089};
RN [1] {ECO:0000313|EMBL:SCX79084.1, ECO:0000313|Proteomes:UP000199089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XBB2008 {ECO:0000313|EMBL:SCX79084.1,
RC ECO:0000313|Proteomes:UP000199089};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMVL01000003; SCX79084.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5AMK8; -.
DR STRING; 1520826.SAMN02910292_00028; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000199089; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000199089}.
FT DOMAIN 200..571
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 443..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 221..228
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 719 AA; 83343 MW; 7BA6DCA98005F5F8 CRC64;
MSIPEEERFL EEVLALIDEK MRELAEKVDI TDKDMADFHE YFWNSYTEFD EYGYELYDNT
NAIRQKIMQK ADFIRERYTY SRMKDSPYFG RVDFVFDGEK TETPCYIGIS NLSKSTGAMP
LIYDWRAPIS SLFYDYDAGP ASYKAPLGTI TGTITHKYQY KISGGRIVYM LESDMNIDDE
ILRAELGTHA SASLKAIVTT IQKEQNAIIR DTDHRILAVQ GCAGSGKTSV ALHRIAYLLY
HNRNTLKASQ VLIISPNGVF ADYISRILPE LGEENICEMS LDVWAYRKLR KIGEAQDRYD
RLEEILTPDM HIPLATDESE YKQSREYVEE LDGYILDLES SAVDIRDYRY RGRKYSASYI
TSLFYEKLWD VPLMERMSRV AEFIIDEEET LRGRDMSAEE KLYITDGLNA MYSDRDLLSL
YNTFLEESGR DAINVTLVIN DDRNTGSDDN DKDSDPDFDE NGNIRYVRPK DEYLKADVIP
YEDVYPILYL KYSLFSQEPA RPVKHLIIDE MQDYTYLQYR LIEKIFPCPM TILGDKAQTI
DEKHRDVLEF LPSIFGRELY TVELNRSYRS TVEITDYAAR IAGLDTYSNI DRHGEEVSEH
IYDNDEELIS QLCEMIKHYA PEQDTIAILC RDASRAADIH RKITASYGEK EDGLEVSLLR
ADTSSFKTGV SIAPFYLTKG LEFDTVFIVD EPFEPEDFHK QALYIEATRA LHVLHIFKK
//
