ID A0A1G5AVD6_9FIRM Unreviewed; 631 AA.
AC A0A1G5AVD6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Xylan 1,4-beta-xylosidase {ECO:0000313|EMBL:SCX81859.1};
GN ORFNames=SAMN02910371_00048 {ECO:0000313|EMBL:SCX81859.1};
OS Butyrivibrio sp. INlla14.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=1520808 {ECO:0000313|EMBL:SCX81859.1, ECO:0000313|Proteomes:UP000199551};
RN [1] {ECO:0000313|Proteomes:UP000199551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INlla14 {ECO:0000313|Proteomes:UP000199551};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865}.
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DR EMBL; FMVS01000002; SCX81859.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5AVD6; -.
DR OrthoDB; 9801455at2; -.
DR Proteomes; UP000199551; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd08989; GH43_XYL-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199551}.
FT DOMAIN 445..623
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 132
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 292
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 244
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 631 AA; 71874 MW; E92DCEB3C5E312DC CRC64;
MDVGNINIYE AARKGDFELV KWIVEYSRAS LNEFDEKHRT ALFYAAISGH LEMFRYLVDR
CGLDPLMGDD DLTTPWDIVH SRIKEIEGSK QPCSNEEFLN NLKEIEDYLE KKYGHKYEDY
YRNPIRPGFF PDPSICRVGS DYYMVNSSFI FFPCIPISHS KDLVHWEIIG HAITNPKWAL
LDELEGGRGY WAPDITYYNG KFYIAATYRL NDSGPVYRRQ IVVSSDKPEG PYSEPVFIDE
DGIDPGLFND DDGRRYMLLN RGARIFELDD TGTKKISDAR LLYYGSNKRA PEGPHIYKKN
GYYYLLQAEG GTGLGHRVTV ARSRELFGVY EPCPYNPIMR QNDEEAAIQR CGHGDLVETP
DGRWFMVYLC GRQIGNGYSI LGRETALDPV TWTADGWPIV NNLKGPSCMQ VKPFADADFT
NQGKIESENT GKDTISPCGL PMDYMTPRGF YPGDVSFKGN KFYIRGSKAP LSSVDSRNIV
LRRQDSFKFK YSAILKPLDL KEGQSAGITG YYDENTYLEF GIVKKDGMLY IYSNEHIGED
DNIFYGEKAL KAEFCGIELV MTTDMLVRTL SYRLLPSSEL TTFNTLSDVY YLCDEGYHIG
KRFTGALVGM YAYGGKESLT AVFEFPLYVS L
//
