ID A0A1G5B0I3_9PROT Unreviewed; 702 AA.
AC A0A1G5B0I3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216308_101490 {ECO:0000313|EMBL:SCX83649.1};
OS Nitrosospira sp. Nsp13.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855332 {ECO:0000313|EMBL:SCX83649.1, ECO:0000313|Proteomes:UP000198731};
RN [1] {ECO:0000313|EMBL:SCX83649.1, ECO:0000313|Proteomes:UP000198731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp13 {ECO:0000313|EMBL:SCX83649.1,
RC ECO:0000313|Proteomes:UP000198731};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMVD01000001; SCX83649.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5B0I3; -.
DR OrthoDB; 8552871at2; -.
DR Proteomes; UP000198731; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17580; REC_2_DhkD-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}.
FT DOMAIN 176..246
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 249..301
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 326..544
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 572..690
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 18..56
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 292..322
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 621
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 702 AA; 78937 MW; 8A50F424BE81EF23 CRC64;
MIDDNEEKLL RSVALQTCNT ILLARQRAEN ELKQAKKSLE EKARRLDHSL SILRATIEST
ADGILVTDQD GLVLRFNELY LQMWQIPRDI PNLSDHRQLL KFCCKCAKNP QWLMEETEGI
YTSWPADSYD VLELADGRVF EQFSKIQYIE NQSIGRVWSF RDITARRHAE DALRESGERQ
HFMAESMPLK IFTARADGVV DYFNQQWKDY TGLPLEQMEC WENTKLIHPD DLDENTRRWR
HSLATGEPFQ MEIRLRQADG GYRWHLTRAH AKCDALGKVS MWVCSSTDID SIKRADEEKK
QLLESERAAR NEAERANRMK DEFLATLSHE LRTPLNAILG WAQLISQGTM NQETVRRGLE
TIERNARMQN KLIEDLLEMS SIISGKIRLD VQQLNLASIA EAALESLAPA AEAKDIHLIK
KIDPAAGLVS GDYNRLQQII WNLLSNAVKF TPKGGNIEVI VERVASYLEI TVKDSGIGVK
PEFLAYIFDR FRQADSSLTR HYGGLGLGLS IVKQLVALHG GTVHAESAGE GLGASFIVSL
PLASVGDRRD QRMAASAAQA PRNRYITLSG IRILVIDDET DSRELINEVL TECDADVITA
ASAAEGLELL QSSRPDVIIS DIGMPEKDGY QLIREVRNLP AAHGGKTPAI ALTAFARSED
RTRAMIAGYQ MHLSKPVESH ELIATIGSLS KWTRKPRIEG EA
//
