ID   A0A1G5B3T2_9FIRM        Unreviewed;       581 AA.
AC   A0A1G5B3T2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Cell wall-associated hydrolase, NlpC family {ECO:0000313|EMBL:SCX84762.1};
GN   ORFNames=SAMN02910371_00183 {ECO:0000313|EMBL:SCX84762.1};
OS   Butyrivibrio sp. INlla14.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio.
OX   NCBI_TaxID=1520808 {ECO:0000313|EMBL:SCX84762.1, ECO:0000313|Proteomes:UP000199551};
RN   [1] {ECO:0000313|Proteomes:UP000199551}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=INlla14 {ECO:0000313|Proteomes:UP000199551};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
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DR   EMBL; FMVS01000002; SCX84762.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5B3T2; -.
DR   OrthoDB; 9812962at2; -.
DR   Proteomes; UP000199551; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:SCX84762.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199551};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        220..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          454..581
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          133..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          258..289
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        9..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   581 AA;  65873 MW;  4A91E203B2441CCC CRC64;
     MNEGVYTRDT SKTQKRIEPG QTPKKKTHAG KLKKEASRAE YARKKLRVGK ADITLTKEEK
     EELKKLRKQG RKKIYADAAV TRSVHSEVRS KNEDNNAGVD AVNAGAEAAE DIGYGVRSRL
     TDSKTEKEYL SKLQEKSTKT ENGYSKKIHN RTGKEEVKRS SKEVQKNLMR KEIQRHAHEV
     QAKESANAFG SIAKRFTDKA EDIAGRLAEM IKEFAENHPL GLLIAVLILI VILVLSGTLS
     SCSMMAGGSN DLVVGTSYTA DEADIVAAEA DYQELEADLQ EQIDNIETDY PDYDEYNYDL
     TEIGHDPFEL AALLTVLYED YTEAEVQTML QTIFEYQYNL EIEEVVETRE REVERSGIRW
     VEDDDYEDGG YWEPYTYTET EEYEYYILNV TLTNEGIQAA IDALDLTVDQ IKRYEVIVEL
     KGNKPDVFGD APYLNPGTPN PYDDYDVPGE YLTDAQFARM LAEAERYLGY PYVWGGSNPS
     TSFDCSGYVS WVINNCGNGW NYGRLTANGW KNVTARVRES DVKPGDLIFF QGTYNTVGAS
     HVGIVVDPIN KIMIHCGSPI KYASYDTRYW RAHFYCYGRI R
//