ID A0A1G5CKD9_9FIRM Unreviewed; 276 AA.
AC A0A1G5CKD9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=5-proFAR isomerase {ECO:0000256|ARBA:ARBA00031376};
GN ORFNames=SAMN02910371_00784 {ECO:0000313|EMBL:SCY02856.1};
OS Butyrivibrio sp. INlla14.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=1520808 {ECO:0000313|EMBL:SCY02856.1, ECO:0000313|Proteomes:UP000199551};
RN [1] {ECO:0000313|Proteomes:UP000199551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INlla14 {ECO:0000313|Proteomes:UP000199551};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SIMILARITY: Belongs to the HisA/HisF family.
CC {ECO:0000256|ARBA:ARBA00009667, ECO:0000256|RuleBase:RU003657}.
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DR EMBL; FMVS01000005; SCY02856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5CKD9; -.
DR OrthoDB; 9807749at2; -.
DR Proteomes; UP000199551; Unassembled WGS sequence.
DR GO; GO:0003949; F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity; IEA:InterPro.
DR GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd04723; HisA_HisF; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011858; His6-like_euk.
DR InterPro; IPR006062; His_biosynth.
DR InterPro; IPR044524; Isoase_HisA-like.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR NCBIfam; TIGR02129; hisA_euk; 1.
DR PANTHER; PTHR43090; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR PANTHER; PTHR43090:SF2; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR Pfam; PF00977; His_biosynth; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU003657};
KW Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102,
KW ECO:0000256|RuleBase:RU003657}; Isomerase {ECO:0000313|EMBL:SCY02856.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199551}.
SQ SEQUENCE 276 AA; 30272 MW; 3634E4D1B95CAA8C CRC64;
MRFRPCIDIH NGRVKQIVGS SLQDAGDKAT ENFSSLKGAD FYARMYRELG LSGGHIIMLN
PVESPYYEST KRQALAALSA TPGLLQIGGG INSDNAQDFL DAGASHVIVT SYAFKNGKIN
KTNLKRLVKA VGKEHIVLDL SCKAAFVDKD GNPVERESID KADNSRKYFV VTDRWQKLTS
VELNKETLDD LSQYCDEFLI HAADVEGRQN GVEENVVRIL GDWGKIPVTY AGGVHTIEDI
GIVRKLGKNR VDITVGSALD IFGGSLKLDE VIKNCI
//
