ID A0A1G5CQL3_9CLOT Unreviewed; 1805 AA.
AC A0A1G5CQL3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SCY04753.1};
GN ORFNames=SAMN03080606_00738 {ECO:0000313|EMBL:SCY04753.1};
OS Alkaliphilus peptidifermentans DSM 18978.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Alkaliphilus.
OX NCBI_TaxID=1120976 {ECO:0000313|EMBL:SCY04753.1, ECO:0000313|Proteomes:UP000198636};
RN [1] {ECO:0000313|EMBL:SCY04753.1, ECO:0000313|Proteomes:UP000198636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18978 {ECO:0000313|EMBL:SCY04753.1,
RC ECO:0000313|Proteomes:UP000198636};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMUS01000003; SCY04753.1; -; Genomic_DNA.
DR STRING; 1120976.SAMN03080606_00738; -.
DR OrthoDB; 9805474at2; -.
DR Proteomes; UP000198636; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000198636};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..266
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 736..769
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1491..1622
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 1805 AA; 211631 MW; BE8A9DCD399849B3 CRC64;
MELINNRYRI EDIKEQESLY SKYIVQDLLQ KNKKVILYII NHTQYSNEFI TFCNNNFYEL
TSIQHPNLLQ VYNYGIIETI DDKRINDRRF YYTTEYYDTE SLINHNIQLS EEEILNVYTK
AALVLDYLHF HGHIYKFIGI DTMFVFRHEN DINIKLLDLV SLKKYEINKR YLDEMSISCR
APELTYGIEL GSYTDIYSLG ALFFYLYTNQ EFQYHKLINR MNHFEKTEVN SREYLLFETF
KKMTHLDFFE RYQSIHELNR HVKEVFRLDG LIEDKSPLEK LNFKTPIIGR DVELKKILDI
QEQSHKNLML IHGDKGIGKT RFVSEVRNQM RWKGYKTFGT TVTSSNENFY KLSAGILKGI
LKITTSNIIH KYANELIKII PEIGANKNII PARPLSEGKE ILKLYDRVSN FIIEGTANQP
TLIIIDDFQY VDHTVAEFID YLLKISKLKK APITVLLSFI KDELTNESIM NYIEQWQRND
YTLETRLSRL TVEETAKVIK HILGWNQEPL NFATRVMKEA DGIPAYIEEA MRELFAQKMI
IVDYSTKFDG FAWHKTTDDY SQIKITDNID EAAVKQFETF DQLTKNIVKI ISLFNTSVSL
EIITAILGEE DDISNHLRRL TQLRILNEKL EDWGYTYGFF RKEFKGYIYN TIDEDLRIEL
HLSVSTVLED LYMREGRENK DELIYHLLQS NQREKAIDYC IDAGDRMYDL KIHSQALVFY
MRAHSLINES VDKRKLYLLI KIGDVYQNQG KNKEAVEYFT EATKLATVND VELIIDAKIR
IGFIALYRNE LIEAEKCFLE CIENAEAYGY NEGLLRTAYL LTRVYMFSRR IDKMSEICTK
YLDVARELNR DDYIGMFLSQ VGVNYSYKGK EVKALSLFKE SVVYLEKANK IEDTCRPINN
IGVILQDHFQ DSKQARDYLE KSLKIAQQYH RVEDVIVTYN NIADSYMIDY EFNKAIEVLN
KNVLLALEYE EETIKILSYI NLVECYIDIC DYKSAYNYLV KTRNEHQAKT GGLYRANFLL
VSCRFYFEMG QYKKAKEIIN EYFTEFNENE SRQYLLMKKL EFMTLSLNKE PMEDKYLFEV
IEQYSNTNYV RDHRLILLEA AMYYCDRNQL DLARDLLAKD EVLIEEYNNE YFQILRIFLK
AIAKNQDNLI SFIEESIIPF VSVNSKELKS KIYKKLAEAY LEKQDYYRAA TYYFSVLEII
QLIINRIPDE FKKSYFLRED KYQVNHQLFI MKEVILNKKF NDTNTTLDTD NLEEYINLDD
FFDISKFQEL FNNPAFYQLA LEQYKNLFPI EVENTMDLIE SLTNDIDYNL DLSIKLAGKL
VLATRGILIG IAEEGYEIIT SFGEKIDLKS INYILEKSST IREGLIVENS FIQPLDGNDD
SQKDSRALMV VPIINKNKGV QTIETEQRNF ARYEQEKIAG FLYLETDKVF NNFSHDTLKE
CEELVPLLGI MLNNYYLKIS SSIDKLTGTY IRKYFEKVLQ DEIEYSKDYE HIFSIIMCDI
DHFKSVNDTY GHQRGDLVLT EVGHIIKNNI RSTDYAGRYG GEEFIILLPR ASKMDALLVA
EKIRTGFSDA KLLGDDVELT ISCGIASYPH DGVNKDTIIE RADQALYTAK EQGRNQSVVW
EDGIRFVNKR VDKLAGIVTG NIVQDQRNVL VLAEAVEIIT EDYSIEEKIY TLLGRLIEIL
EAEDGILFIV KNNEILTQFG RKRFIDEWIK TYSYNNKLIE KVIQTKQGEY LIDWEDVSHI
DIFTGAPNWK SVIATPIIFN GELQGIVYLA VSVKEKEFDF SGYNLAKLTS NILGAVITDY
NYITE
//
