ID A0A1G5DW41_9ACTN Unreviewed; 387 AA.
AC A0A1G5DW41;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DNA-binding transcriptional regulator, GntR family {ECO:0000313|EMBL:SCY18956.1};
GN ORFNames=SAMN02745898_1011167 {ECO:0000313|EMBL:SCY18956.1};
OS Streptomyces sp. 136MFCol5.1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1172182 {ECO:0000313|EMBL:SCY18956.1, ECO:0000313|Proteomes:UP000199326};
RN [1] {ECO:0000313|Proteomes:UP000199326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=136MFCol5.1 {ECO:0000313|Proteomes:UP000199326};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMVI01000001; SCY18956.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5DW41; -.
DR Proteomes; UP000199326; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR PANTHER; PTHR43537:SF46; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF13551; HTH_29; 1.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SCY18956.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199326};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 170..237
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 42345 MW; 3532072744498838 CRC64;
MTVPDPQAFP QLSEEDRAAL SDYSRQPPGA LRLRSSIVLA CAEGLTNTEV AQRLQVSPAT
VAKWRDRYLR RGMAGLSDAP RSGRPRSVTR QGAEAHIAAV LAQAENGSPV PSTRALSDTL
GLSQSTVARI WREQAAGLSE PPRPRNGKRG PGAEQDGDGP APVPARIPRQ LLSDQVYTLL
RDWIVSGELV PGQRLVESEI ARRVGTSQTP PREAIKRLAY EGLVVSQPHR GTRVARISER
QAQDVRDIRV MFEEYVARRI AGRLDAEHTR LLADDVAQLR RAVNKGDIAA FRSADMSFHR
HVCEAARNDA LIRLWRMIES SLWDLHVLGD PRYVGGWGAL AEHHAELLDV LRSGDPDVAG
PMFAAHAAGE VDRYLPDQAE PGAPSGQ
//
