ID A0A1G5E227_9PROT Unreviewed; 339 AA.
AC A0A1G5E227;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=6-phosphogluconate dehydrogenase (Decarboxylating) {ECO:0000313|EMBL:SCY21024.1};
GN ORFNames=SAMN05216308_105224 {ECO:0000313|EMBL:SCY21024.1};
OS Nitrosospira sp. Nsp13.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1855332 {ECO:0000313|EMBL:SCY21024.1, ECO:0000313|Proteomes:UP000198731};
RN [1] {ECO:0000313|EMBL:SCY21024.1, ECO:0000313|Proteomes:UP000198731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp13 {ECO:0000313|EMBL:SCY21024.1,
RC ECO:0000313|Proteomes:UP000198731};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; FMVD01000005; SCY21024.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5E227; -.
DR OrthoDB; 9804542at2; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000198731; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 2.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064}.
FT DOMAIN 184..339
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 339 AA; 36427 MW; 3410C6C6F5EE688B CRC64;
MQLGMIGLGR MGINMVGRLM KAGNECVVYD PRAEAVQTSR SQGAVGTSSL EELVARLATP
RVIWLMVPAA LVDEILSKIA SLVEAGDIII DGGNSYYHDD IRRGAEMRSR GIHYVDVGTS
GGIAGLERGY CLMIGGEKEI VHHLDPIFAA LAPGIDAAPR TPGRQDSEGT AEQGYLHCGP
HGAGHFVKMV HNGIEYGLMA AYAEGLNILH SANAGKRVQD MDAETTPMRN PEFYQYELDL
PEIAEVWRRG SVVASWLLDL TAEALIDDAE LTEFSGRVSD SGEGRWTTLA AVDEGVPVPV
ISAALFSRFE SRGNADYADR LLSAMRKQFG GHGEKKAGG
//
