ID   A0A1G5EKP6_9FIRM        Unreviewed;       349 AA.
AC   A0A1G5EKP6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:SCY27545.1};
GN   ORFNames=SAMN05660668_02025 {ECO:0000313|EMBL:SCY27545.1};
OS   Pseudobutyrivibrio sp. AR14.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Pseudobutyrivibrio.
OX   NCBI_TaxID=1520804 {ECO:0000313|EMBL:SCY27545.1, ECO:0000313|Proteomes:UP000198746};
RN   [1] {ECO:0000313|EMBL:SCY27545.1, ECO:0000313|Proteomes:UP000198746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR14 {ECO:0000313|EMBL:SCY27545.1,
RC   ECO:0000313|Proteomes:UP000198746};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMUY01000010; SCY27545.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5EKP6; -.
DR   OrthoDB; 9814210at2; -.
DR   Proteomes; UP000198746; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
FT   DOMAIN          294..349
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   349 AA;  39348 MW;  EA3F9B3349B44830 CRC64;
     MRFNYQDMVA GGKKPYVIAE LGANHNGDME LAKTMIKTAK ECGADCIKLQ SFTKSNVFSK
     KNYEDNYFLG DDYRNRTDYT LESIVEAYAL TREQHFELKA YCDELDIDFT STPFDKAGVD
     LLVDELHVPF IKVASMDVEN VPFLKYIGSK GVPVVISTGL TGMDDVVNAI AAIEAGGCKE
     ICVLHCVSIY PPADEQVNLN NIDMYRMAFG YPTGYSDHTF GVVAPIMSIA KNVCIIEKHF
     TMDKNMKGWD HKISANPEEM KIICDAAEQG YKMMGSYRKI VNESEHQRGE YKRSIVAAHD
     MKAGHILTED DLDYKRPGTA ISPKFYEMLI GKELKRDITA DELFQWGDF
//