ID   A0A1G5EZA2_9FIRM        Unreviewed;       261 AA.
AC   A0A1G5EZA2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase {ECO:0000313|EMBL:SCY32297.1};
GN   ORFNames=SAMN05660668_02193 {ECO:0000313|EMBL:SCY32297.1};
OS   Pseudobutyrivibrio sp. AR14.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Pseudobutyrivibrio.
OX   NCBI_TaxID=1520804 {ECO:0000313|EMBL:SCY32297.1, ECO:0000313|Proteomes:UP000198746};
RN   [1] {ECO:0000313|EMBL:SCY32297.1, ECO:0000313|Proteomes:UP000198746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR14 {ECO:0000313|EMBL:SCY32297.1,
RC   ECO:0000313|Proteomes:UP000198746};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMUY01000012; SCY32297.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5EZA2; -.
DR   OrthoDB; 9807064at2; -.
DR   Proteomes; UP000198746; Unassembled WGS sequence.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   CDD; cd16442; BPL; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00121; birA_ligase; 1.
DR   PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR   PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR   Pfam; PF03099; BPL_LplA_LipB; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SCY32297.1}.
FT   DOMAIN          74..261
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
SQ   SEQUENCE   261 AA;  28418 MW;  F3F7E0BBDDA41BDC CRC64;
     MASKDKVLEL LESNKETYIS GEVIASSLGL SRNAIWKAIN ELRKAGYEID AISNKGYKLK
     EGNDILSEAG IISYLNSSYK SKYKGSNLIR IYDVANSTNR IAKEMAIAGA AHGTVVIANE
     QTEGRGRKDH SFYSPKGGLY LSIILRPEFL KTLLPDEITI QTGTAVCDSI EALAGVRPTL
     KPINDLFIND KKICGILTEA GTEFETGDIQ WIVVGIGINF DSDISAFPSD IKNIATSLFS
     PNQATITRNQ LAAEIIQKIV V
//