ID A0A1G5GIF4_9FLAO Unreviewed; 420 AA.
AC A0A1G5GIF4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Hemolysin, contains CBS domains {ECO:0000313|EMBL:SCY51274.1};
GN ORFNames=SAMN02927903_01592 {ECO:0000313|EMBL:SCY51274.1};
OS Flavobacterium caeni.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=490189 {ECO:0000313|EMBL:SCY51274.1, ECO:0000313|Proteomes:UP000199354};
RN [1] {ECO:0000313|EMBL:SCY51274.1, ECO:0000313|Proteomes:UP000199354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7031 {ECO:0000313|EMBL:SCY51274.1,
RC ECO:0000313|Proteomes:UP000199354};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FMVF01000006; SCY51274.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5GIF4; -.
DR STRING; 490189.SAMN02927903_01592; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000199354; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000199354};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 55..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..191
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 270..330
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 420 AA; 48077 MW; 0E0E6F8FC784D9BF CRC64;
MHLGIIITCL ILAAFFSGME IAFISANKIY LEIEKKQDGF LSRILTRLTA DPSRFIVSML
IGNTIALVVY GFFMGELVVR WLADSGYHFS GIVRLLLQIL AATVVVLLTS EFIPKVLFQI
YANSLIKFFA LPAYLFHWLF SYVSRLSLWV SNRILRVFFK TEGDKIPLFF SKAELGNYIT
EQMSTVEDHE EVDSEIQIFQ NALEFSGVKA RDIMTPRTEI SAVEIYDSVA ELREMFIETG
YSKILVYQNS LDDILGYVHS FDLFKKPRTI KSVMIPVEFV PETIFIKDTL ELLTKKRKSV
AIVLDEYGGT AGMVTVEDIV EELFGEIEDE HDAVEEELTE QELGPNVWLF STRLDVEYLN
ETYKLEIPED DSYSTLGGFI VFHTKEIPQK GEEIAVENFH FSIAEATNKK IELVKMTRRD
//
