ID   A0A1G5HAI1_9FIRM        Unreviewed;       724 AA.
AC   A0A1G5HAI1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Sigma-B regulation protein RsbU (Phosphoserine phosphatase) {ECO:0000313|EMBL:SCY60717.1};
GN   ORFNames=SAMN02910292_02215 {ECO:0000313|EMBL:SCY60717.1};
OS   Lachnospiraceae bacterium XBB2008.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1520826 {ECO:0000313|EMBL:SCY60717.1, ECO:0000313|Proteomes:UP000199089};
RN   [1] {ECO:0000313|EMBL:SCY60717.1, ECO:0000313|Proteomes:UP000199089}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XBB2008 {ECO:0000313|EMBL:SCY60717.1,
RC   ECO:0000313|Proteomes:UP000199089};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FMVL01000008; SCY60717.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5HAI1; -.
DR   STRING; 1520826.SAMN02910292_02215; -.
DR   OrthoDB; 9763484at2; -.
DR   Proteomes; UP000199089; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199089};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        391..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          411..465
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
SQ   SEQUENCE   724 AA;  79579 MW;  CAE6FD168D36A3D4 CRC64;
     MKKIKNLVIG GIQNKVFNLV LITIILMIGV FAAVAVYEFR VLSRIFEETH QRQKTSILTL
     SSQTMDGVVN SSLSTTTDLE AYMADDMFSE LKSEVSLLAE YAEDIAQNPE NYGAAHVARP
     QKGLVGTVTV QLATASGVDV NSPEVDRAVK LFGNMSEVLK ATYNNMNINS CYISTPEGIM
     IVADPYSGDR VDDDGNYVTI ESTERSWYKG AVEAGDTYFS DIMTDTFNGR KTIVCSKPVY
     YKNGDLAGVV GIDLYLDSMA DAVAQSVKDG TFVYIVNNRG HIVFSPMTSG TFKAEIETEA
     PDLRESENAD LAAFISDALE GKTDIRQIDA DGNTWYMSGA PLPTIGWALI NAVDKSVTDQ
     PTVLIEEQYE KYLEEAAVGF RDSQESSKTT VLLLLGLVFV IALAMGTSLG TRMVKPLNTL
     SKRIGELGED NLQFKMEDGF RTGDEIEVLA QSFADLSRKT VQYINEVTRV TAEKEHIEAE
     LDMAKAIQAS QLPNTFPAYP ERGEFDIFAS MTPAKQVGGD FYDFFMTDDD HIVLVMADVA
     GKGVPAALFM MVSRILIKNR LCTGESPGEA LYNVNNQLLE GNEAELFVTV WLAVIEISTG
     KGVSVNAGHE HPALRHAGGK YELVEYKHSP AVSVMEGLKY KEREFKLEPG DSIFVYTDGV
     AEATDIEDQL FGSERLLEAL NEDPDADPTK ILENVKRHID DFVAGEEQFD DITMLAFKYI
     GSKG
//