ID A0A1G5HWS8_9FIRM Unreviewed; 1169 AA.
AC A0A1G5HWS8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=DNA helicase/exodeoxyribonuclease V, subunit B {ECO:0000313|EMBL:SCY67929.1};
GN ORFNames=SAMN02910292_02451 {ECO:0000313|EMBL:SCY67929.1};
OS Lachnospiraceae bacterium XBB2008.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1520826 {ECO:0000313|EMBL:SCY67929.1, ECO:0000313|Proteomes:UP000199089};
RN [1] {ECO:0000313|EMBL:SCY67929.1, ECO:0000313|Proteomes:UP000199089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XBB2008 {ECO:0000313|EMBL:SCY67929.1,
RC ECO:0000313|Proteomes:UP000199089};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMVL01000010; SCY67929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5HWS8; -.
DR STRING; 1520826.SAMN02910292_02451; -.
DR OrthoDB; 9758506at2; -.
DR Proteomes; UP000199089; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR049035; ADDB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR PANTHER; PTHR30591; RECBCD ENZYME SUBUNIT RECC; 1.
DR PANTHER; PTHR30591:SF1; RECBCD ENZYME SUBUNIT RECC; 1.
DR Pfam; PF21445; ADDB_N; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000313|EMBL:SCY67929.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199089}.
FT DOMAIN 5..273
FT /note="ATP-dependent helicase/deoxyribonuclease subunit B
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21445"
FT DOMAIN 794..1130
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
SQ SEQUENCE 1169 AA; 131191 MW; 6B6DAA97D4558E8D CRC64;
MSFKLICGPS GSGKSTYIQQ NIIKRSIDDP GRKYLLIVPD QFNMQTQMSM IRNHPDHAFS
NIEVLSFSRL SHRILEETGG EVPVLDDTGK SLILRRLSGS VRPQMSVLGA RLDRYGFIHE
VKSAVSEFMQ YGISPEDLHE MCARIDGRGA LKAKMSDLEI IYRAFTDYKA GHYVTKEETL
ELVRSSLHKS KLVRDAFIAF DGFTGFTPIQ ERVIQELMGI CDSVWFAFTT EDGADPHKEL
KSDDMFHLSW RSVDRIGRLA DEANVPEEEP VILRAGTVPF DGKTDVKFDG KSDGKAGPVR
KSADLIHLER SLFRFPTRPY SGEAGHIRIY KASGMSEEIV DTFQRIRELI SERHYRYRDI
AIVVGDMEAY ADEISRTAAE LDMPVYMDYS KSILMSPFIE AIVSSYDVLK TDYSCESIIR
HMRTGYGPLS MEETDELENF LLATGIRGRN AYSHTWTMRD RDDAELSEAA LSIRKERFDR
LNAIREKVNA HFISLHNTEE TIGSYSRAVY SFISGAGMYG RLMKQAAQFR EEGDHVRALQ
YEQMYEHVCA LLDQIVELCG DEEVSADDYF HILEAGLSEI RLGTIPGESD RIMVGDIIRT
RLEAVKILFL LGVSDDSIPG NVSGGGLISD LDREYLSEMD GVELAPTPRE QMFTQRLYLY
MNMTKPSDGL IISYPMTDTG GKAKQPSYLI STLCKLFPSL TPVPSARTHM VDESVAPADR
TRVSYTCADM MREYYGGRLN GDEQSRLKAI CDEMENSSDA GLLDKISDMS TVHYKHTPLT
REIASALYGS IIRTSVSRLE RFAGCAYAHF LNYGLRLRTR SEYSFENADL GVVYHKALEE
FSVKVNDEGL TWAGLSEAEA DRWVDEILER LINTYGDTIL TSSSRNAALA SRIRRIVKRS
VDTIRYQVTR GGFVPRYFER AFSEERKAQT PDGKPFGYKV SGKIDRIDIC ESEEAHYLRI
VDYKSGSRDF DISALFHGLM MQLAVYLDQA LKITDDTKPA GMLYFRISDP VIEASADISG
ESALAAVRKE MKMSGIVEAS PKVTGLMDSE LAPGVSSDIV PVGYKADNTL TKASKAYSGE
NIRTILDFAE YKMDELTGSI MFGDISVRPA CMKGSAYTPC TYCDYASVCH IASGIPGYEG
IQYGKEEPQD VINAMKSALH RNEDDTSPE
//
