ID A0A1G5LVG9_9ACTN Unreviewed; 344 AA.
AC A0A1G5LVG9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=CBS domain-containing protein {ECO:0000313|EMBL:SCZ16491.1};
GN ORFNames=SAMN02745898_11774 {ECO:0000313|EMBL:SCZ16491.1};
OS Streptomyces sp. 136MFCol5.1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1172182 {ECO:0000313|EMBL:SCZ16491.1, ECO:0000313|Proteomes:UP000199326};
RN [1] {ECO:0000313|EMBL:SCZ16491.1, ECO:0000313|Proteomes:UP000199326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=136MFCol5.1 {ECO:0000313|EMBL:SCZ16491.1,
RC ECO:0000313|Proteomes:UP000199326};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
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DR EMBL; FMVI01000017; SCZ16491.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5LVG9; -.
DR OrthoDB; 9789996at2; -.
DR Proteomes; UP000199326; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000425; MIP.
DR PANTHER; PTHR48108:SF6; CBS DOMAIN-CONTAINING PROTEIN CBSX1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR48108; CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199326};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 214..271
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 279..337
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 344 AA; 36012 MW; 049710B2C09426E1 CRC64;
MSVLPYIVAQ LIGSVLGVLS ARAVRGAAVE NPPVAKATLH SGLGWSAGEL FAAETATMGL
IVYAIGFFLQ TPKLAPLVPW LAGLLIAAVI ALLGTATGGS VNPARQFGRR WSLGNSASCG
STCSPPWWGL RSRPPSWAGC AGTAPCSPIG CAAPTPTAPP CDGLSNERCN QSAAFWTQTS
RSLLSEWRHA WGAVYRLFRT PEPEKLMELV RDAMTTRCVT VPPYTSLTAV AACMRDDNVG
CVMVTHDGAL QGIITDRDIT VRITAEGLIA GTTTAQQAAS KSLVTVVPGA TLCDAAALMC
MHSFHRLPVV EQGQLVGLLS LGDICETPHA QEILVALSQA EANH
//
