ID A0A1G5P9X9_AFIMA Unreviewed; 679 AA.
AC A0A1G5P9X9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=SAMN03080610_03617 {ECO:0000313|EMBL:SCZ46304.1};
OS Afifella marina DSM 2698.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Afifellaceae; Afifella.
OX NCBI_TaxID=1120955 {ECO:0000313|EMBL:SCZ46304.1, ECO:0000313|Proteomes:UP000199347};
RN [1] {ECO:0000313|EMBL:SCZ46304.1, ECO:0000313|Proteomes:UP000199347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2698 {ECO:0000313|EMBL:SCZ46304.1,
RC ECO:0000313|Proteomes:UP000199347};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; FMVW01000013; SCZ46304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5P9X9; -.
DR STRING; 1120955.SAMN03080610_03617; -.
DR OrthoDB; 7211215at2; -.
DR Proteomes; UP000199347; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF68; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000199347}.
FT DOMAIN 226..496
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 247..254
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 679 AA; 74960 MW; 2544074DFA718DC4 CRC64;
MTLRIADSFT ASLAKLTPQE QGLVKQTAFD PHSGLDRPGL SLRRVDGARD KGFWTARVND
DIRIVLHRRG EDTLLAYVGH HDDAYRWAER RRLDVHPKTG AAQLVEIRER VEEVVVPVYV
AGEAAKPKLF AETPEATLLL CGVPEDWIGD VREVDEDTIF ALAEHLPAEA MEALLNLAVG
IEPVVAFMQK LDPFAHPDAR RRFHLLTDET DLRRALEAPW ETWSIFLHPA QREFVERDFA
GPARVIGSAG TGKTVVALHR AVRLARENPA ARILLTTFNS LLATALHLKV KTLVGDETPV
LERITVADLP SAARELFERT VGPIRLADAE DVARALAKAK AASDLSVDGR FLLEEWKLIV
DGRQIQDRET YRDLPRLGRK KRLAGERREA LWTIFEDARE SLRAAGLTTY AEMLRLLADG
ITAAEVPFDY IVVDEAQDIL AAELRILGKL AGDRPNGLFF AGDIGQRIFR PAFSWRSEGV
DVRGRSRSLR VNYRTSQQIR RQAEGLLPSM LVEADGSEDD RLGVQSLFSG ATPVVRVFPD
IEGEKEAVAA WLSQCVSEGM EPSAIALVVR SPELFERAEA AAALAGLRSS QDGEKGSAVR
VAAMHDVKGL EFRAVAVMAC EEGVVPSEAR MVEAADEGAL AEVYATERHL LYVACTRARE
NLLVTAAEPA SEFLQDLHS
//
