ID   A0A1G5PTI7_9GAMM        Unreviewed;       963 AA.
AC   A0A1G5PTI7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:SCZ52389.1};
GN   ORFNames=SAMN03097708_00741 {ECO:0000313|EMBL:SCZ52389.1};
OS   Thiohalomonas denitrificans.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiohalomonadales;
OC   Thiohalomonadaceae; Thiohalomonas.
OX   NCBI_TaxID=415747 {ECO:0000313|EMBL:SCZ52389.1, ECO:0000313|Proteomes:UP000199648};
RN   [1] {ECO:0000313|EMBL:SCZ52389.1, ECO:0000313|Proteomes:UP000199648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HLD2 {ECO:0000313|EMBL:SCZ52389.1,
RC   ECO:0000313|Proteomes:UP000199648};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; FMWD01000002; SCZ52389.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5PTI7; -.
DR   STRING; 415747.SAMN03097708_00741; -.
DR   Proteomes; UP000199648; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02783; MopB_CT_2; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.30.200.210; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR   PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199648}.
FT   DOMAIN          13..69
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   963 AA;  108495 MW;  4DF2AB1F4234FD99 CRC64;
     MSDMAKNATE GRTEVKNTTC YMCACRCGIR VTLRDGEVRY IQGNPDHPLN KGVICAKGSS
     GIMKQYSPAR LTRPLKRKAG ADRGDAQFEP ISWDEAFGML EERLAHIRET DPKKFALFTG
     RDQMQALTGL FAKNFGTPNY AAHGGFCSVN MAAGMIYTIG GSFWEFGGPD LDRAKLFVMI
     GTAEDHHSNP MKMALSKFKR NGGRFISVNP VRTGYSAIAD EWIPIKPGTD GALMLALTHE
     IIKTGLYDRE FLIQYSNAAE LVNLNEESPE HGMFVRFEVP PEEGCFDPQN KLWWDRELNK
     PISTHTPGAD PYLLGDFRLS DGTPVKPSFQ LLKERVEEYT PEWAADITGI PAETIRRLAH
     EMGITARDEK IELPIAWTDT WGNEHQSVTG NPVAFHAMRG LAAHSNGFHT IRAMSILMSI
     LGTIDRPGGF RHKAPFPRPI PPCPKTPTGP EDVKAGQPLN GMPLGWPADP DDLFVDDKGQ
     PVRIDKAFSW EHPLSVHGMM HNAITNAWRG DPYSIDTLLI FMANMSWNSS MNTDEVRKML
     NDKDENGEYK IPFLVVADAF QSEMVAYADL VLPDTTYLER HDVMSMLDRP ISEFEGPVDS
     VRIPVVPPKG ECKPFQEVLI ELGSRLKLPP FTHEDGSRKF RDYPDFVTNF ETAPGSGIGF
     LAGWRGKGGE KSIRGEPNPN QWEMYAKNNC VFQHELPKSY QYMRNWNQGY LQWAQEHGMT
     RYAEPINVHI YSEVLQKFRL AAQGKTQGKQ PPDNLRRRID LFFDPLPFYF EPLESQLSDK
     QAYPLNAITQ RPMAMYHSWD SQNAWLRQIH TYNFLHLHPK TAEAAGIEDG GWMWVESMHG
     KVRCMARYSE AVEPGTVWTW NAVGKASGAW NLDDDANEAR QGFLLNHVIA EELPAHDAGK
     HISNSDPVTG QAGWYDVRVR VYPAGPDEEK VSWPQFTPMP QVPGTGERRP WLNYVAGLFE
     KRG
//