ID   A0A1G5S4U6_9FIRM        Unreviewed;       636 AA.
AC   A0A1G5S4U6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SCZ81385.1};
GN   ORFNames=SAMN03080599_02767 {ECO:0000313|EMBL:SCZ81385.1};
OS   Acidaminobacter hydrogenoformans DSM 2784.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales;
OC   Eubacteriales Family XII. Incertae Sedis; Acidaminobacter.
OX   NCBI_TaxID=1120920 {ECO:0000313|EMBL:SCZ81385.1, ECO:0000313|Proteomes:UP000199208};
RN   [1] {ECO:0000313|EMBL:SCZ81385.1, ECO:0000313|Proteomes:UP000199208}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2784 {ECO:0000313|EMBL:SCZ81385.1,
RC   ECO:0000313|Proteomes:UP000199208};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FMWL01000018; SCZ81385.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5S4U6; -.
DR   STRING; 1120920.SAMN03080599_02767; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000199208; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199208};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          282..565
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   636 AA;  70986 MW;  D0595FF5FA78D9BB CRC64;
     MRTTRKLSIM LLDIGFLFAS MLAAIVLKAD FERLFHLFEN APHFILLMIG IKLVFLKLLM
     LYDSLWEHAS VDELIRIAVF GALSHFTVVA LDLYMDGEFS YKSLLLISFF DVVLIGGFRM
     SYRVLRRLMS RASNITQSYK SVLIIGAGHT GGMTARHLLS EPQRLGYPKA FIDDDPLKEG
     TLVSGIKVLG NRYDILSVVK RQKIDEIILA IPTVPMQDRR EILSECKRTG VKVKTVPSLE
     EMMVDNVDLK KIRDVEIEDL LGRDEVNLDM AGIKDYLEGK TVLVTGGGGS IGSELCRQIL
     RFAPKKLIIL DINENAVYDL SNELKARGLA GVDLDTVITS VRDRKELQRA FQTLKPQVVF
     HAAAHKHVPL MERSPQEAIK NNVFGTMNLV DAALKNDVER FVLISTDKAV NPTSVMGVSK
     RIAEMIVQSV ESNKTIFTAV RFGNVLGSNG SVIPLFKKQI QAGGPVTVTH KDMVRYFMTI
     PEASRLVLQA GGLAKGGDVF VLDMGEPVRI LNLAEDLIRL SGLEPYKDIE IEFTGLRPGE
     KLFEELLTSE ESVESKTKHE KIFVGKPGRV EYAILLKRLV LLKELAEGGD QEALLEMLAS
     LVTSYQRDNR EINKAFLENG CTALIKEMKS RKLAMS
//