ID A0A1G5SA32_9CAUD Unreviewed; 661 AA.
AC A0A1G5SA32;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DNA gyrase subunit A {ECO:0000313|EMBL:SCZ84033.1};
DE EC=5.99.1.3 {ECO:0000313|EMBL:SCZ84033.1};
OS Enterococcus phage VFW.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Andrewesvirinae; Vipetofemvirus.
OX NCBI_TaxID=1813888 {ECO:0000313|EMBL:SCZ84033.1, ECO:0000313|Proteomes:UP000278763};
RN [1] {ECO:0000313|Proteomes:UP000278763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Duerkop B.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrA/ParC subunit
CC family. {ECO:0000256|ARBA:ARBA00008263}.
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DR EMBL; LT546029; SCZ84033.1; -; Genomic_DNA.
DR Proteomes; UP000278763; Chromosome vfw.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR InterPro; IPR035516; Gyrase/topoIV_suA_C.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013758; Topo_IIA_A/C_ab.
DR InterPro; IPR013757; Topo_IIA_A_a_sf.
DR InterPro; IPR002205; Topo_IIA_dom_A.
DR PANTHER; PTHR43493:SF5; DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR PANTHER; PTHR43493; DNA GYRASE/TOPOISOMERASE SUBUNIT A; 1.
DR Pfam; PF00521; DNA_topoisoIV; 1.
DR SMART; SM00434; TOP4c; 1.
DR SUPFAM; SSF101904; GyrA/ParC C-terminal domain-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:SCZ84033.1};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 5..442
FT /note="DNA topoisomerase type IIA"
FT /evidence="ECO:0000259|SMART:SM00434"
FT COILED 414..441
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 661 AA; 75695 MW; A19967D46756EAC2 CRC64;
MINKVGLGEQ LNDAMMGMSA YTILQRAIPD FRDGFKPVNR RIITSMLLNK TFNFTKSATV
EGRVMQLHPH GGSYGSIVGL VQKDRNSLPF LTGKGSWGQY TSSDQQPAAA RYTEVKLGKN
ALEVTKELKE KSVDYVPNYD GTISVPEVLP VTYPSILTQS QSGIANGFAT SILSYNIHEL
YDMIDDILML RGRTKPIYPD FPTGATIIKD DEEALNVIRT GRGSFTMRAK IEIDNNKLIV
TEIPYGVKRE QIIKKIIELN KRGTLKEVTD VRDGTSFKGM KIVITAKKNT DMKELIVKLY
KLTPLQSKVS ANMNVLIDGR LEVLGVEELL LNWIKWRVSV IKRGLNNKLT SMKKELHILE
GLRKIASVDE VIRIVRFEDD DKVDQLLMEA FNLTKEQAEY IGKMTLRSLN EKRIQNRLKD
IEDLENKIKD LEETIDNDGL LKVILQRRMM ETMKEIDAPK RKTEIITIDE EKEKEVHKIV
KVKEVDNTKH FVCFTKNGWL LKGKNKNDME SQLILGDEIV QYWEAQNDKN IVLFMKDKSV
RNIKVKQIKE KEFIGNDALF AECNVDEKAL MLLVFDEGHI VKIPIDAFVK NRQVMEKGYF
DGEKLIYVKQ LSDEKMINIY IGDKKPKTIE IENINIKKNR LARGQKLFNN KKLEKVNVTL
G
//
