ID   A0A1G5UST9_9SPHN        Unreviewed;       450 AA.
AC   A0A1G5UST9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN   ORFNames=SAMN03159340_03816 {ECO:0000313|EMBL:SDA36713.1};
OS   Sphingomonas sp. NFR15.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1566282 {ECO:0000313|EMBL:SDA36713.1, ECO:0000313|Proteomes:UP000199327};
RN   [1] {ECO:0000313|Proteomes:UP000199327}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NFR15 {ECO:0000313|Proteomes:UP000199327};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; FMWX01000011; SDA36713.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5UST9; -.
DR   STRING; 1566282.SAMN03159340_03816; -.
DR   Proteomes; UP000199327; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR034474; Methyltransferase_Class_D.
DR   InterPro; IPR007197; rSAM.
DR   PANTHER; PTHR43306; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43306:SF1; 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN DIMETHYLTRANSFERASE; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDG01100; methyltransferase_(Class_D); 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199327};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          70..283
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
SQ   SEQUENCE   450 AA;  49995 MW;  4DDD8A6499C113FB CRC64;
     MPTKIIVEGD LVFYRKRCRV HGVTKTVISD DVGYWRAAKD WLKPGDRPLA IHSRTDHGCP
     FDCGLCADHE QHSCLALIEI NEACNLSCPV CFAGSSIHHL GHRPLAEVEA MLDVIVAAEG
     EPDLVQISGG EPTIHPQFFE ILQAARRRPI RHLMVNTNGL RIAREPDFVA RLAAFRPRFE
     IYLQFDALDD EALMVLRGAR LSSMRRRALE ALEAAGISTT LVVTVKKGVN DQQIPDIVRH
     ALEWRCVRGV TFQPVQDTGR NDGFDAKQHR ITLTEIRRRI AEAGVFALGD LIPLPCNPDQ
     ICIGYGLRNG RDVAPVTAML PRELFVAAAP NTVSFEAYPE LKDRIFQLLS LSTAQADTSE
     KLASLLCCLP EAAVPEEIGY AQTFRVVISQ FLDRFNFDLG TVKRSCVHFV QPDGAIIPFD
     TFNLFYRPGA AGEAVLADAK VNHRRVRSIA
//