ID A0A1G5UU32_9FIRM Unreviewed; 406 AA.
AC A0A1G5UU32;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=23S rRNA (Cytosine1962-C5)-methyltransferase {ECO:0000313|EMBL:SDA37154.1};
GN ORFNames=SAMN02910343_00051 {ECO:0000313|EMBL:SDA37154.1};
OS Allisonella histaminiformans.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Allisonella.
OX NCBI_TaxID=209880 {ECO:0000313|EMBL:SDA37154.1, ECO:0000313|Proteomes:UP000199689};
RN [1] {ECO:0000313|EMBL:SDA37154.1, ECO:0000313|Proteomes:UP000199689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15230 {ECO:0000313|EMBL:SDA37154.1,
RC ECO:0000313|Proteomes:UP000199689};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
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DR EMBL; FMXA01000003; SDA37154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G5UU32; -.
DR STRING; 209880.SAMN02910343_00051; -.
DR OrthoDB; 9805492at2; -.
DR Proteomes; UP000199689; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:SDA37154.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199689};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDA37154.1}.
FT DOMAIN 5..90
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 406 AA; 45831 MW; 2431C52EB6827018 CRC64;
MEALKTVTIS KRAELAAKGG HPWIYGSEIK GKDEGIEPGE IVRVLSGKGK FIGSGFYNEH
SKITVRIIST NANDRFDDAF WKRRVSYALD YRLQVMRPED YDNMRIIFGE ADQLPGLTVD
RFGDVLSVQV LSLGIEKNKD IILNSLIEVL RQHGLPVSCV YERNDVKIRE LEGLTQYKGF
FDSPLLNPED RKTITHIVEN GIHYDVDVEN GQKTGFFLDQ KFNRLAAGSI ARGRHVLDCF
THTGAFALNA ARGGAASVTA VDISAEAVAM VKHNAECNHL EIEAVEADVF EYLTELDRTH
NHTYDYIILD PPAFTKSRQT VHEAFRGYKE INYRAMKILP RGGYLATCSC SHFMGEELFI
KMLKEAARDA GVTLKQIESR QQAPDHPILM SVPETYYLKF FLFQIV
//
