ID   A0A1G5UUC8_9SPHN        Unreviewed;       385 AA.
AC   A0A1G5UUC8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:SDA36716.1};
GN   ORFNames=SAMN03159340_03819 {ECO:0000313|EMBL:SDA36716.1};
OS   Sphingomonas sp. NFR15.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1566282 {ECO:0000313|EMBL:SDA36716.1, ECO:0000313|Proteomes:UP000199327};
RN   [1] {ECO:0000313|Proteomes:UP000199327}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NFR15 {ECO:0000313|Proteomes:UP000199327};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; FMWX01000011; SDA36716.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5UUC8; -.
DR   STRING; 1566282.SAMN03159340_03819; -.
DR   OrthoDB; 9806939at2; -.
DR   Proteomes; UP000199327; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   PANTHER; PTHR30469:SF37; RAGD PROTEIN; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199327};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          79..298
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
SQ   SEQUENCE   385 AA;  39787 MW;  2C211BFDF8C4C505 CRC64;
     MQAEPVQAPA PKGLKTAGVV AVVAAIGVVA AGAMVRRGDT QTAQAWSDAR SVPTVHLVAA
     KGASASDALT LPGTMQAWNA AKLYARVGGY VSAWYKDIGA SVGAGTPLGR IDTPELDQQI
     ASARAALVSA QAHASLARST AARWNDLLTD NSVSKQEADE KNGDLAVRTA AVQAARADLG
     RLLAQKAFST VRAPFAGTVT SRNADIGDLV GPGASVQQPM FSVADTRKIR IYVNVPQNYS
     AGMTPGLTAT LTTPDYPART FNAHVIGNSG AINQQTGTFQ VQLIADNADG ALKPGGYAQV
     KFDVRGQTGT VQIPSSALIF RAQGTQVATV GADRHIHLRP VTIGRDLGPS VEITSGLSAA
     QKIVDNPPDS LADGELVRVE DKTHG
//