ID   A0A1G5UUI2_9SPHN        Unreviewed;      1072 AA.
AC   A0A1G5UUI2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SDA36717.1};
GN   ORFNames=SAMN03159340_03820 {ECO:0000313|EMBL:SDA36717.1};
OS   Sphingomonas sp. NFR15.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1566282 {ECO:0000313|EMBL:SDA36717.1, ECO:0000313|Proteomes:UP000199327};
RN   [1] {ECO:0000313|Proteomes:UP000199327}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NFR15 {ECO:0000313|Proteomes:UP000199327};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMWX01000011; SDA36717.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G5UUI2; -.
DR   STRING; 1566282.SAMN03159340_03820; -.
DR   Proteomes; UP000199327; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF8; CATION EFFLUX PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199327};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        432..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        459..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        550..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        892..911
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        923..940
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        946..972
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        993..1013
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1025..1048
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1072 AA;  113824 MW;  42689AA582597209 CRC64;
     MLQLVKLALS KPYTFVVLAI LIVLGGSIAW VRTPTDIFPD IKIPVIAVVW TYRGLPPEDM
     AGRVVYYYER QLSSTVNDID HIESQSLNGV GIVKIFFQPG VDIRTASAQV TAASQTVLKQ
     MPPGITPPQI LNYNASTVPI LQLALSAKDL SEQKIYDLGQ NFIRPALASV QGAAIPSPYG
     GKERQIQIDL DPDALQARHL SASDVGAALA AQNQIVPAGT TKIGQYEYNV RLNNSPEVVA
     QLNDLPIKTV DGATVLMRDV AHVRDGSPPQ RNVVRVDGGR AVLMTVLKSG AASTIAIVDQ
     AKALLPKIRE TLPPSLKVQP LSDQSLFVKA AVSGVIKEGV IAAALTSLMI LLFLGSWRST
     VIIAASIPLA ILAAVAGLAM AGQTLNIMTL GGLALAVGIL VDDATVTIEN INWHLEQGKS
     VRAAILDGAE QIVGPAFVSL LCICIAFLPM FFLPGVAGFL FAPMAMAVVF AMIASFVLSR
     TLVPTMGNYL LRTHATEHTA EVMVSHDAKA GRPGSRNVFR RFQSGFEHRF EKVRGYYVSL
     LDFALARRRV FVPVFMAVVL LSFALVPMLG RNFFPTIDAG QINLHVRAPI GTRIEETAAL
     FDHVEDRIRS VIPPDELVSI VDNIGMPVSG INRAYSNTGG VGPQDGDILV TLSEGHKPTA
     GYVRALRKTL PDAFPGSVFS FLPADIISQI LNFGAPAPID VMVTGSDIKG GKAYAQALAE
     KMQHIPGIAD VRVQQTEAYP ELGFDVDRAQ ANRLGITEND VTRSMAVNLA GSFQVAPAFW
     LNPKNGVSYP IVVQTPQYRT DSLSALQNLP ITGSSGTYQL LGALGTLHRE PSPAVVTHYA
     VQPSYDVYAT TQGRDLGAVA ADIRAVLDGA KATLPKGSSV KLRGQVETMN TAFSGLIFGL
     IGAIVLIYLL IVVNFQSWVD PTVIISALPA ALAGIVWMLF ATHTPLSVPA LTGAIMCMGV
     ATANSVLVVS FARERLAATG DALRAAAEAG ATRFRPVLMT ALAMIIGMAP MALGLGEGGE
     QNAPLGRAVI GGLICATLAT LVFVPVVFSI AHRKHRRAAS DPLATGSLAH AG
//