ID A0A1G6AHU8_9FIRM Unreviewed; 605 AA.
AC A0A1G6AHU8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN02910298_00287 {ECO:0000313|EMBL:SDB07965.1};
OS Pseudobutyrivibrio sp. YE44.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Pseudobutyrivibrio.
OX NCBI_TaxID=1520802 {ECO:0000313|EMBL:SDB07965.1, ECO:0000313|Proteomes:UP000198713};
RN [1] {ECO:0000313|Proteomes:UP000198713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YE44 {ECO:0000313|Proteomes:UP000198713};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FMXT01000001; SDB07965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6AHU8; -.
DR STRING; 1520802.SAMN02910298_00287; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000198713; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDB07965.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 325..378
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 485..593
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 366..398
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 605 AA; 68734 MW; 658E36A084A61A70 CRC64;
MKSIDFYNQY KRVRRASKRR SIQLIISLSF TIVSILSMAF ITMAFYTTYI NTARETAIEN
NKQVIDQMSW TLNSYLRNMM GVSNSMYYGV IKNMDLTSDT MNKEMDILYE ANKDDLISIA
CISQDGALIS AAPISTRKSG VDFTEQEWFT STEEKIENFH FSKPHVQNMF EGSNYRYYWV
VSLSRSVDLN YMGYARRGIL LVDMNYSAIE QMFSRVNEKG SGYVYLIDGD GEIIYHPKQK
AISGGLMQEN NIAAAEYDDG GHMENFEGSE RAVVVKTIGY TGWKIVSVVP ASELSAPYNQ
LRAFMMIIVT VTIFLIVFGN IIISKIVTDP IRQLEASLKS IEEGSLEAQK VYIGGSHEIR
HLGRTIRSLV VQMRDLMDER VKEQKEKRKS ELNALQAQIN PHFLYNTLDS VIWMIESEKY
PEAISMITSL ATLFRISLSK GNNIITIKDE ITHARNYLAI QKVRYKNKFD ANIDIDPAIE
DCVTIKLIIQ PLIENAIYHA VGDLDDEGII DIKGYEKDGD IFIEVRDNGM GIPPDVLENL
LKEKSQSKGK GSGIGLWNIN QRINLYFKND YGLKLESELD EGTVAIIHLP KMTMEEYLGG
EGNAK
//
