ID   A0A1G6ALS1_9FIRM        Unreviewed;       329 AA.
AC   A0A1G6ALS1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Nitroreductase {ECO:0000313|EMBL:SDB09073.1};
GN   ORFNames=SAMN02910317_00473 {ECO:0000313|EMBL:SDB09073.1};
OS   Ruminococcaceae bacterium FB2012.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX   NCBI_TaxID=1520817 {ECO:0000313|EMBL:SDB09073.1, ECO:0000313|Proteomes:UP000199364};
RN   [1] {ECO:0000313|EMBL:SDB09073.1, ECO:0000313|Proteomes:UP000199364}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB2012 {ECO:0000313|EMBL:SDB09073.1,
RC   ECO:0000313|Proteomes:UP000199364};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the nitroreductase family.
CC       {ECO:0000256|ARBA:ARBA00007118}.
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DR   EMBL; FMXS01000003; SDB09073.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6ALS1; -.
DR   STRING; 1520817.SAMN02910317_00473; -.
DR   OrthoDB; 9783470at2; -.
DR   Proteomes; UP000199364; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd02062; Nitro_FMN_reductase; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   PANTHER; PTHR43673; NAD(P)H NITROREDUCTASE YDGI-RELATED; 1.
DR   PANTHER; PTHR43673:SF10; PROTEIN DRGA; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   Pfam; PF00881; Nitroreductase; 2.
DR   SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199364}.
FT   DOMAIN          158..213
FT                   /note="Nitroreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00881"
FT   DOMAIN          219..301
FT                   /note="Nitroreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00881"
SQ   SEQUENCE   329 AA;  36762 MW;  6490407599BE9B18 CRC64;
     MIYSAMVNKA IKVMFEAHKD QRDKSGLPYV FHPFHLAEQM KDEVTTAAAL LHDIIEDTDM
     TADGLRELGF PEKVVRIVEL LTHKDGESYE DYIERIKTDP GARAVKVADL RHNSDMTRLE
     TVTQGDIDRA EKYRRAIKVL SGEDAENGNR GSEILEAISR RRSYRGKYKS RAVPRDDLRK
     IMQAGLDAPS GCNKQTVSLI AVDDSEILAR LKAVIDPPVA ETAPAAICVL TNRETAYRDK
     CFAVQDYAAA IENMLLAIEA LGYRSCWYEG HITDDDDIAG KMAKILEVPE GYEIVCFLPV
     GIAEEEPVMP KKKEFGERVL PRTAAGAWS
//