ID A0A1G6B2T5_9STRE Unreviewed; 250 AA.
AC A0A1G6B2T5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Adapter protein MecA {ECO:0000256|HAMAP-Rule:MF_01124};
GN Name=mecA {ECO:0000256|HAMAP-Rule:MF_01124};
GN ORFNames=SAMN02910293_00751 {ECO:0000313|EMBL:SDB14763.1};
OS Streptococcus henryi.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=439219 {ECO:0000313|EMBL:SDB14763.1, ECO:0000313|Proteomes:UP000182508};
RN [1] {ECO:0000313|EMBL:SDB14763.1, ECO:0000313|Proteomes:UP000182508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-4 {ECO:0000313|EMBL:SDB14763.1,
RC ECO:0000313|Proteomes:UP000182508};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Enables the recognition and targeting of unfolded and
CC aggregated proteins to the ClpC protease or to other proteins involved
CC in proteolysis. {ECO:0000256|HAMAP-Rule:MF_01124}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738, ECO:0000256|HAMAP-
CC Rule:MF_01124}.
CC -!- DOMAIN: The N-terminal domain probably binds unfolded/aggregated
CC proteins; the C-terminal domain interacts with ClpC.
CC {ECO:0000256|HAMAP-Rule:MF_01124}.
CC -!- SIMILARITY: Belongs to the MecA family. {ECO:0000256|ARBA:ARBA00005397,
CC ECO:0000256|HAMAP-Rule:MF_01124}.
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DR EMBL; FMXP01000008; SDB14763.1; -; Genomic_DNA.
DR RefSeq; WP_074485594.1; NZ_FMXP01000008.1.
DR AlphaFoldDB; A0A1G6B2T5; -.
DR STRING; 439219.SAMN02910293_00751; -.
DR eggNOG; COG4862; Bacteria.
DR Proteomes; UP000182508; Unassembled WGS sequence.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.1950; -; 1.
DR HAMAP; MF_01124; MecA; 1.
DR InterPro; IPR038471; MecA_C_sf.
DR InterPro; IPR008681; Neg-reg_MecA.
DR PANTHER; PTHR39161; ADAPTER PROTEIN MECA; 1.
DR PANTHER; PTHR39161:SF1; ADAPTER PROTEIN MECA; 1.
DR Pfam; PF05389; MecA; 1.
DR PIRSF; PIRSF029008; MecA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000182508}.
SQ SEQUENCE 250 AA; 28718 MW; EECF8FFDB1018A04 CRC64;
MEMKQISETT LKITISMEDL EEHGMELKDF LIPQEKTEEF FYNVMDELDL PDNFKNSGML
SFRVTPRKDR IDVFVTKSEI NKDLNFEDLA DLGDVSNMSP EDFFKTLEQS MRSKGDTDAH
EKLEKIEEIM EAVADEAMNE QAVEESEEAV EPADYVHYVL DFASLEDAVL FSKTVDFPVE
ASELYKQSDA YHMTVLLNLV NKPSYFANVM YARMLEHAAP GTKTRAYLQE HGVQLLMDDA
VQKLQLIDLV
//
