ID A0A1G6BCT1_EUBOX Unreviewed; 371 AA.
AC A0A1G6BCT1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SDB18339.1};
GN ORFNames=SAMN02910417_01364 {ECO:0000313|EMBL:SDB18339.1};
OS Eubacterium oxidoreducens.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1732 {ECO:0000313|EMBL:SDB18339.1, ECO:0000313|Proteomes:UP000199228};
RN [1] {ECO:0000313|EMBL:SDB18339.1, ECO:0000313|Proteomes:UP000199228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3217 {ECO:0000313|EMBL:SDB18339.1,
RC ECO:0000313|Proteomes:UP000199228};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; FMXR01000009; SDB18339.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6BCT1; -.
DR STRING; 1732.SAMN02910417_01364; -.
DR Proteomes; UP000199228; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199228};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 248..371
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 371 AA; 42850 MW; 62A6BF0361210D72 CRC64;
MFFLANDEVE VEQSEELNEY IRKSEREIEA KWRKIHFNML LLVSVCIIIC EVLVSLLLLV
KSDMISHLER YIIRYLLVPG SSYLIIDLIA YFGMKKLNRQ GWKLNYLLSV LLAVMCVLIS
LYHAVFPSVY GLGILAIIMT FIYGNHKIGL TTMLVVLCGG FASFTFLPWD HDVTHGIVYD
ISAFIMFVAS IGVYILGGAV VVWEQQFRRN AIMGNYKLDN LKKVAARDYL TGVRNRFGMQ
KYIEQLNGTC RCVMLDVDYF KKVNDRWGHD LGDQILENLG EILERYERMD RAFFRYGGDE
FLCIVQNHTI SELTSICDEI VASFEQLLGM DLKKEKISIT YGISPEVDVM EIQSGIMMAD
KELYKRKKAR Y
//
