ID A0A1G6BGH5_9FLAO Unreviewed; 1248 AA.
AC A0A1G6BGH5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN03097699_0044 {ECO:0000313|EMBL:SDB19705.1};
OS Flavobacteriaceae bacterium MAR_2010_188.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1250295 {ECO:0000313|EMBL:SDB19705.1, ECO:0000313|Proteomes:UP000199442};
RN [1] {ECO:0000313|EMBL:SDB19705.1, ECO:0000313|Proteomes:UP000199442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mar_2010_188 {ECO:0000313|EMBL:SDB19705.1,
RC ECO:0000313|Proteomes:UP000199442};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LT629302; SDB19705.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6BGH5; -.
DR STRING; 1250295.SAMN03097699_0044; -.
DR Proteomes; UP000199442; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07494; Reg_prop; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF101898; NHL repeat; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SDB19705.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199442};
KW Transferase {ECO:0000313|EMBL:SDB19705.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 935..953
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1007..1248
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1248 AA; 141214 MW; EDD20ADCC978BBFF CRC64;
MKPIFYSRPL QIYCITVLFL AIFSCNQKER AVPFPENENE YSRPADSPLQ FSEPKKIEWS
VNDTTNFKAA TVKKVNLENL PSKPFYPDGF LPLNNPIEEI NFDFTTLPDT LINIKELASK
PIRFKTSIIE PPLSVPAGLP KLKKNASMGI LEFGEDQGLP GYLVTAMMED SYGMMWIGSD
KGLCRFNGEY IEIYSFIDNI FTGALAEISS MLEDNKGRIW IYTSQKGIYV LDLKAGVVRN
ANFIKQEFNF NPDCSMVMDS RGFIWLGTIQ DGFYILNPSN ETYRHVSQLQ PQDNGNAKRI
LEDSSGNIWI SSIAGLSIID YDKGRIRFLN SSEELSMPSA TAFFNDRKNR IWVGTEDNGI
SILDLEHDKI QNLGSSQGFT NSIQHFTQGN DDKLWMSTAA GVYVFDVEKQ RLQQLTANKG
LSDNLINTTY FDRLGQIWIA TSSALNLMDT EGLMPKFLTA ADGLSGPDVW SFFEDNKAHL
WIASRQGIDI YDPLSNTIRE VDHELGLNKA PNISYKILPM PTGEYLIVSP RFGLGIFSPE
LQTIRIIGTE QGLNIPIPSS SLVDHRGHIW NGSFQNGTVE YMDSDTNTFK LFTNKNGLVG
DIVWELMEDD KGQIWVATDK SINIINVADN TISQLMENGK ISERNGGAFL RDAKDRMWIA
TRSGILIADQ NKGTLTSLNT ENGLVHKAVY TLYENEGKIY AGTENGFTVF TPKSEEELDD
TFSYEVKSFG KGQGLKYTDF NAGAAIVYED KLWWGIETQA MTISNIPKEK STTSIAHIVG
ITISDEPQTF YEYRTILQNY PKLDTLYTSK KDTFYISEKI PKESGGLREN NISWDSLDGY
YNLPVNLKIP FEQNYLSFQF TGAQLTNIDK TRYRYILEGF DTEWSEITEI SNSKNYRNLA
AGDYLFKVRS RTADGIWSEP AEMSFTILPH WTNTWWAWSL YVLAFIIVVG MIAQYRARLL
KKENLILEEK VKHRTAQLNK SVEDLKATQS QLIQSEKMAS LGELTAGIAH EIQNPLNFVN
NFSEVSNELI QEIQAERTKQ KENRDEKLVE EILVDIQENL EKINHHGKRA DAIVKGMLQH
SRNSSGEKRL TDINALCDEY TRLSYHGLRA KDKSFNADIK TDFDENISKV EINQQDIGRV
ILNLVNNAFY AVHEKKIKTN DKDYKPLVQI STQLDSGGII IQVKDNGNGI PDKVKEKIFQ
PFFTTKPTGK GTGLGLSLSY DIIKAHNGQI NVETVEGENT KFTIFLPC
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