ID A0A1G6CFL6_9STRE Unreviewed; 535 AA.
AC A0A1G6CFL6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=SAMN02910293_01560 {ECO:0000313|EMBL:SDB31512.1};
OS Streptococcus henryi.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=439219 {ECO:0000313|EMBL:SDB31512.1, ECO:0000313|Proteomes:UP000182508};
RN [1] {ECO:0000313|EMBL:SDB31512.1, ECO:0000313|Proteomes:UP000182508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-4 {ECO:0000313|EMBL:SDB31512.1,
RC ECO:0000313|Proteomes:UP000182508};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMXP01000021; SDB31512.1; -; Genomic_DNA.
DR RefSeq; WP_074486267.1; NZ_FMXP01000021.1.
DR AlphaFoldDB; A0A1G6CFL6; -.
DR STRING; 439219.SAMN02910293_01560; -.
DR eggNOG; COG1418; Bacteria.
DR eggNOG; COG4372; Bacteria.
DR Proteomes; UP000182508; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000182508};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 351..444
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 104..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 60301 MW; B5479311F2C0DF92 CRC64;
MLTVVLTIVF ALIGLILGYA LISIRLKSAK EAAELTLLNA EQDAVNLRGK AELEADHIRQ
SAERETKAHR KELLLEAKEE ARKYREEIDK EFKSEKQELK QMEARLTERA SSLDRKDENL
TSKEKALDSK EQSLTDKSKH INEREVKISE LEKQKQVELE KVAMMTIAEA REIILTDTEN
KLTHEIASRL KEAEREIKDK SDKTAKNILA QAMQRMAGEY VTEQTITTVH LPDDSMKGRI
IGREGRNIRT LESLTGIDVI IDDTPEVVVL SGFDPIRREI ARMTLEALIA DGRIHPARIE
ELVEKNRLEM DNRIREYGEA AAFEIGAPNL HPDLIKIMGR LQFRTSYGQN VLRHSVEVGK
LAGILAGELG ENVDLARRAG FLHDMGKAID REVEGSHVEI GTEFARKYKE HPVVVNTIAS
HHGDVEPESV IAVLVAAADA LSSARPGARN ESMENYIKRL RDLEEIATSF EGIQQAFALQ
AGREIRIMVQ PNKVSDDQVT VLAHKVREKI ENNLDYPGNI KVTVIRELRA IDYAK
//
