ID   A0A1G6DCH8_9FIRM        Unreviewed;       310 AA.
AC   A0A1G6DCH8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Cation:H+ antiporter {ECO:0000313|EMBL:SDB42565.1};
GN   ORFNames=SAMN02910317_02116 {ECO:0000313|EMBL:SDB42565.1};
OS   Ruminococcaceae bacterium FB2012.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX   NCBI_TaxID=1520817 {ECO:0000313|EMBL:SDB42565.1, ECO:0000313|Proteomes:UP000199364};
RN   [1] {ECO:0000313|EMBL:SDB42565.1, ECO:0000313|Proteomes:UP000199364}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB2012 {ECO:0000313|EMBL:SDB42565.1,
RC   ECO:0000313|Proteomes:UP000199364};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FMXS01000011; SDB42565.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6DCH8; -.
DR   STRING; 1520817.SAMN02910317_02116; -.
DR   OrthoDB; 9794225at2; -.
DR   Proteomes; UP000199364; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   InterPro; IPR004481; K/Na/Ca-exchanger.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   NCBIfam; TIGR00367; calcium/sodium antiporter; 1.
DR   PANTHER; PTHR10846:SF8; INNER MEMBRANE PROTEIN YRBG; 1.
DR   PANTHER; PTHR10846; SODIUM/POTASSIUM/CALCIUM EXCHANGER; 1.
DR   Pfam; PF01699; Na_Ca_ex; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199364};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        76..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        258..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          3..142
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
FT   DOMAIN          169..308
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
SQ   SEQUENCE   310 AA;  33018 MW;  32DA6AD6B942E8EA CRC64;
     MQYLLLVAGF VLLIKGADFF VDGSSGLAKR LKVPSMIIGL TVVAMGTSLP ETSVSVSASL
     QGKNDLAISN AVGSNIFNLM VVCGVTAIIT PLFIKKESLR REFPFSILCA AVLMVFGLIG
     GEVNRIEGIV LLLMFGGFLA YTVISAKKAR NAFAAEKADD KIMPMWQCLL FIVCGGTAIA
     FGGRMVVNSA SEIARSFGLS DNVIGLTIVA LGTSLPELFT SIVAAKHGEV DIALGNVIGS
     NIFNILFVLG IATTISPISF MMTNTIDCIA LIAMSLIVMI FCWTKQTLQR WEGAVMAAAY
     TAYIVYITLR
//