ID   A0A1G6E8G0_9FIRM        Unreviewed;       378 AA.
AC   A0A1G6E8G0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SDB53691.1};
GN   ORFNames=SAMN02910317_02767 {ECO:0000313|EMBL:SDB53691.1};
OS   Ruminococcaceae bacterium FB2012.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX   NCBI_TaxID=1520817 {ECO:0000313|EMBL:SDB53691.1, ECO:0000313|Proteomes:UP000199364};
RN   [1] {ECO:0000313|EMBL:SDB53691.1, ECO:0000313|Proteomes:UP000199364}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB2012 {ECO:0000313|EMBL:SDB53691.1,
RC   ECO:0000313|Proteomes:UP000199364};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMXS01000018; SDB53691.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6E8G0; -.
DR   STRING; 1520817.SAMN02910317_02767; -.
DR   OrthoDB; 9781904at2; -.
DR   Proteomes; UP000199364; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDB53691.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199364};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        12..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          265..357
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00387"
FT   REGION          353..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          122..149
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   378 AA;  41077 MW;  890E45E9FAAAF8DC CRC64;
     MNKLADKLTV MLLCAAAFTF LDGPVVPVVG LIVSVIVTSF VWLTEGTVFA AAAVAASAVC
     CIFFPVILCA SPIILYDALG EKKPWLAAPL LPAMTGITEL EPHQIVIVFV SLTVTVIYRR
     RVSLLEKSVE NLSSLRDEVE EKNLLLNEKN LSLADAQDNE IYLATLRERN RIAREIHDNV
     GHMLTRSLLQ AGALTVINKD EKLKAPLDDL KETLNTAMTS IRESVHDLHD ESVDLDAAVR
     ESIRSVGDRF KVTYDNDTEG ELPAKLRLCF LAVIKEGISN AVKHSDGDRI DITIRQHPAF
     YQLTVEDNGS CGEIIPERSG GIGLQNMRDR AASLGGMISI TSSQNGFRIF MTVPQGPSGP
     SADGGRGVPL HPTPPQAT
//