ID A0A1G6EBG7_9FIRM Unreviewed; 566 AA.
AC A0A1G6EBG7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Na+-driven multidrug efflux pump {ECO:0000313|EMBL:SDB54702.1};
GN ORFNames=SAMN02910317_02829 {ECO:0000313|EMBL:SDB54702.1};
OS Ruminococcaceae bacterium FB2012.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=1520817 {ECO:0000313|EMBL:SDB54702.1, ECO:0000313|Proteomes:UP000199364};
RN [1] {ECO:0000313|EMBL:SDB54702.1, ECO:0000313|Proteomes:UP000199364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FB2012 {ECO:0000313|EMBL:SDB54702.1,
RC ECO:0000313|Proteomes:UP000199364};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FMXS01000019; SDB54702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6EBG7; -.
DR STRING; 1520817.SAMN02910317_02829; -.
DR OrthoDB; 9808973at2; -.
DR Proteomes; UP000199364; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002528; MATE_fam.
DR PANTHER; PTHR43823:SF3; MULTIDRUG EXPORT PROTEIN MEPA; 1.
DR PANTHER; PTHR43823; SPORULATION PROTEIN YKVU; 1.
DR Pfam; PF01554; MatE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199364};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 566 AA; 61738 MW; BA6F829A89E0C29D CRC64;
MLISGTFTKA VMYLMLLSDS IIAGFFIGEN GVAGINAITP VTAIVTFFGD LGSTGVGIVF
SREVGAMRKR RADEIFGQGL IISIGLGLIS ALMIFVFQSA YFSASGITGE TLEQATKYYR
LVPINAFLTI VIFYLEQMVY SDGDELCNNI CYGFQIGGNI ICSVILTKFF GMTGIILGSV
IGNSLGILAC LWHFFRRNNT LHFVWHLSFK DFLLTSRYSI VDSSVYICWG LMDYVMIGFI
SRSYGDPGLI ALAVVVSLIE FGVVLDGVGM AMQPLVGTYY GEKNHRLIKR VTKAGIKAAI
AEGAAATLLI MIFAKQFCGL FGVTDGASLT SSVTAIRIVC LGFVFCSLVS LTTSYYMLID
RIAMATCFAC LQNGLLYILL PVLGSLLFGI NGLWAGFVAA PILTLVFAML FVYLRFGKND
FPFLLGDMDT EIVVMDDILS PESVSALSAQ VTDRLISHQY PKKTANRAGL FAEEIGLTVL
DINKQSKKPI LVELSLFFED GQVLIIERDS GKLFDLTDPD AQVSGLSGFV LSGLMEAHKE
KAYLVTTGYN RNMIRFSREP ETAGEM
//
