ID   A0A1G6EKH9_9FIRM        Unreviewed;       375 AA.
AC   A0A1G6EKH9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:SDB57888.1};
GN   ORFNames=SAMN02910317_03023 {ECO:0000313|EMBL:SDB57888.1};
OS   Ruminococcaceae bacterium FB2012.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX   NCBI_TaxID=1520817 {ECO:0000313|EMBL:SDB57888.1, ECO:0000313|Proteomes:UP000199364};
RN   [1] {ECO:0000313|EMBL:SDB57888.1, ECO:0000313|Proteomes:UP000199364}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB2012 {ECO:0000313|EMBL:SDB57888.1,
RC   ECO:0000313|Proteomes:UP000199364};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMXS01000024; SDB57888.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6EKH9; -.
DR   STRING; 1520817.SAMN02910317_03023; -.
DR   OrthoDB; 8435646at2; -.
DR   Proteomes; UP000199364; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199364}.
FT   DOMAIN          6..118
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   375 AA;  42182 MW;  2AF8666CD1FF5381 CRC64;
     MDKPVIFFSH SSKDRDIILP LKDKLGKITS GTVDIFMSSD GQSIPFGSNW IHKVEEGLKE
     ARIMFVFATE TSLSSGWIYF EAGFAYSKGI QVVPVGIGVN IGSLKPPLNL LQGFNITSGD
     SLNNFVSIIN REFSCSFPES FVEDDFYAIK KTIEGDTGGI STIRDFMSGA LFDMVPKYTE
     SDGSKVEHDI DSIYEKIVAY LDSNSIPYSK CTSQNGDTFI TVEGIKLKYH KKFDESKNDF
     FIQNQNNSFI RYSISLYNFE KSFELLKKLV SISGYKSRYI KFLFGANNDC IVTEEDISSI
     ISGNTDLQID RDKPLSFTFA PSDLKAVIGT KQKDNTVVPD KRNYISIVYK EETQVENIVV
     LLNRLHDIGI IYDVN
//