ID   A0A1G6JGH2_9PROT        Unreviewed;      1048 AA.
AC   A0A1G6JGH2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Cobalt-zinc-cadmium resistance protein CzcA {ECO:0000313|EMBL:SDC17829.1};
GN   ORFNames=SAMN04487779_1001166 {ECO:0000313|EMBL:SDC17829.1};
OS   Belnapia rosea.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Belnapia.
OX   NCBI_TaxID=938405 {ECO:0000313|EMBL:SDC17829.1, ECO:0000313|Proteomes:UP000198925};
RN   [1] {ECO:0000313|EMBL:SDC17829.1, ECO:0000313|Proteomes:UP000198925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CPCC 100156 {ECO:0000313|EMBL:SDC17829.1,
RC   ECO:0000313|Proteomes:UP000198925};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
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DR   EMBL; FMZX01000001; SDC17829.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6JGH2; -.
DR   STRING; 938405.SAMN02927895_00353; -.
DR   OrthoDB; 9758757at2; -.
DR   Proteomes; UP000198925; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004763; CusA-like.
DR   NCBIfam; TIGR00914; 2A0601; 1.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF12; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198925};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        449..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        482..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..556
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        873..892
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        899..921
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        927..952
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        973..996
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1002..1025
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1048 AA;  112838 MW;  C0EB86D1AC67F33C CRC64;
     MRQIVAFSLQ RRPLVILLFF TFIVIGLIGF TRLNIEAYPD PVPPQVVIIT QNAGQSAEEI
     ERYVSIPVEV AMAGLPNLTS VRSTSLFGLS DVRVQFNFNY TYDQALQQVL NRLGQLNGLP
     EGVQPQISPL SPIGEIMRYR LVGPPGYSLA DLKTLQEWVL DRRFKRVPGV VDVTSFGGLT
     KSYNVVVDLR RMAALGLSLP QVIQAVRAGN ATVGAGTIRI GPQAAVVQGI GLIRGLDDIR
     SVVVSAEGGM PVLLGDIATV EIGNQPRLGI AGQEGNDDVV LATVLMRRGE QTLPTIRGVQ
     QEVARINAGG VLPPGVKIVP LYDREDLVKI TTRTVVHNII EGVALILLIQ WLFLGDFRGA
     LVVAATVPFA FLFAILLMMA RGESANLLSL GALDFGLLVD ATVIMVENIY RHLGLSRNPA
     HRYIAPASSR DLSGLSLTVL RAAGEVDKAI FFSALIIIAA FIPLFTLGGI EGRIFGPMSK
     TYAYAIIGAL LATFTITPAL AAALLREDSR ERDTLLVRVL RWGHTRLYAA AMRARALCLM
     LAAALFGASI FLMSLLGAEF LPTLEEGNLW VRASMPGTIS LEEGNATVNR IRGVLMEFPE
     VITATSQQGR PDDGTDSAGF FNAEFFLPLK PPQQWTTAPN RDGLVHAMQA RLSSQFVGVE
     FSYSQAISDN VQEAASGVKG ANAVKVFGPE LDIIARKAEE IRQVMAGVEG VADLAVFRSL
     GQPTVALQID RARAARYGLA IDDVNEVVQA AIGGREAGRL YEPGGDRNFP IVVRLDAPFR
     DSLEAIGRIP VGGPRGATLA DVASIRLVSG VSYIYREDAS RYVPIRFSVR GRDPASTVAE
     AQELVEQRVQ LPPGYRLDWV GEFRNLQEAI GRLLVVVPAA LALILVLLYV QFNSLRETLL
     VFGIVPMSIT GGVAALAVAG LNFSVPAAIG FLALFGITVM EGIIMLSHFN HLRLEGMPWR
     PALDQAGRDR MRPVFMTCFA SFTGLLPMAL ATGIGADVQK PLALVVVGGI GLVPLFILVV
     FPAMIDLFGK PRHIRQAEAA APGAAVRA
//