ID   A0A1G6JY63_9BURK        Unreviewed;       623 AA.
AC   A0A1G6JY63;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:SDC22956.1};
GN   ORFNames=SAMN05216345_1011005 {ECO:0000313|EMBL:SDC22956.1};
OS   Cupriavidus sp. YR651.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1855315 {ECO:0000313|EMBL:SDC22956.1, ECO:0000313|Proteomes:UP000198719};
RN   [1] {ECO:0000313|Proteomes:UP000198719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR651 {ECO:0000313|Proteomes:UP000198719};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; FMYZ01000001; SDC22956.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6JY63; -.
DR   STRING; 1855315.SAMN05216345_1011005; -.
DR   OrthoDB; 9764248at2; -.
DR   Proteomes; UP000198719; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd11083; CYP_unk; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   InterPro; IPR017941; Rieske_2Fe-2S.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   PANTHER; PTHR24301; THROMBOXANE-A SYNTHASE; 1.
DR   PANTHER; PTHR24301:SF2; THROMBOXANE-A SYNTHASE; 1.
DR   Pfam; PF00067; p450; 1.
DR   Pfam; PF00355; Rieske; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   SUPFAM; SSF50022; ISP domain; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
DR   PROSITE; PS51296; RIESKE; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW   Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW   ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198719}.
FT   DOMAIN          29..123
FT                   /note="Rieske"
FT                   /evidence="ECO:0000259|PROSITE:PS51296"
SQ   SEQUENCE   623 AA;  68332 MW;  B46B2E40570D0B89 CRC64;
     MNTPGEPLTV GATTAGRYAA PHQGTGDRIR VASAAVLAGG GILPIQVDGV DLVMVGRDGA
     VSAFQGRCPH QGTLLAEGSL EDGILTCRGH GWRFDGTSGI RVGQPDVCLW RFTATLEGDD
     VWMDRAEILA WKARLDARSQ PASDKSETHF SDMPARPLTA LPCPHGLPWL GNALQLRKTH
     LHADLERWGE KFGPIYRFSL MKRAVVVISD GEWIDRILRD RPGTFRRASV IEALSREIGT
     VGVFSAEGEA WLRHRRPVAQ ALDARHLRDF FPTLVNVTRR LQRRWDQAAA EGRSVHAQHD
     LMQYAVDVTT SLAFGHDMNT LEGHGGEVQH HLEHILPMIA RRLNSAFPYW HYIRLPADRA
     FDRSVEAVRA ALGDIIAATR ERLSQAPELA AHPRNFLESM IAAQAAGEAA LSDDELFANA
     FTLLLAGEDT TANTIAWILY IMCLHPEVQR RMQEETGAVL GTADVLTDMQ DAARLVYLDA
     VAHESLRLKP VAPLIYLEPN EDVAIAGYLV PKGTLIVLVT RPNALRESQF AAAGEFRPER
     WLETSAAAHH RSGFVPFGSG PRLCPGRSLA LLEAKAALSM VCQHFTVRLA PASGPVSETF
     AFTMMPTGLR VVLERRQAGA RPV
//