ID A0A1G6K7M2_9BURK Unreviewed; 509 AA.
AC A0A1G6K7M2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Nucleobase:cation symporter-1, NCS1 family {ECO:0000313|EMBL:SDC26933.1};
GN ORFNames=SAMN05444679_102104 {ECO:0000313|EMBL:SDC26933.1};
OS Variovorax sp. CF079.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1882774 {ECO:0000313|EMBL:SDC26933.1, ECO:0000313|Proteomes:UP000198763};
RN [1] {ECO:0000313|EMBL:SDC26933.1, ECO:0000313|Proteomes:UP000198763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF079 {ECO:0000313|EMBL:SDC26933.1,
RC ECO:0000313|Proteomes:UP000198763};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; FMZU01000002; SDC26933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6K7M2; -.
DR STRING; 1882774.SAMN05444679_102104; -.
DR Proteomes; UP000198763; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11555; SLC-NCS1sbd_u1; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR PANTHER; PTHR30618:SF6; PERMEASE-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198763};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 67..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 509 AA; 55674 MW; 18399871CE957DEA CRC64;
MPFGHPPIPH EETPVNTAVS PGSMDLPIAG HAPHTESNAL IKPGYDPALT NEDLAPLKKQ
TWGQYNIFAF WMSDVHSVGG YITAGSLFAL GLSSWQVLVA LLVGICIVQF FCNLVAKPSQ
LTGTPYPVIC RASFGVRGAN IPAIIRGLIA VAWYGIQTYL ASAAFMVLAL HLFPNLAPYA
DVKLHGFAGL SALGWLAFMV MWVLQAFVFW HGMEAIRKFI DWAGPGVYVV MTILCGWLVW
KAGWSRIDLN LGGVKFQGWD ALPVMLSAIA LVVSYFSGPM LNFGDFSRYS KSFDAVKKGN
FWGLPVNFVF FSLLTVITTA ATLPVFGELI TDPVHTVGKI DSTTAVVLGA LTFMIATIGI
NIVANFVSPA FDFSNVAPQH ISWRTGGMIA AVGSIFLTPW NLYNNPEVIH YTLDILGSFI
GPLFGILIAD FYLVRKQQVV VDDLYTLSPK GRYWYSKGYN LKAVWTMIPS ALIPILCVLI
PAWRGAANYA WFIGMGLGFV IYALLNRKP
//
