ID   A0A1G6KKL3_9BACI        Unreviewed;       420 AA.
AC   A0A1G6KKL3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=SAMN05421734_106122 {ECO:0000313|EMBL:SDC31503.1};
OS   Pelagirhabdus alkalitolerans.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pelagirhabdus.
OX   NCBI_TaxID=1612202 {ECO:0000313|EMBL:SDC31503.1, ECO:0000313|Proteomes:UP000242949};
RN   [1] {ECO:0000313|Proteomes:UP000242949}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S5 {ECO:0000313|Proteomes:UP000242949};
RA   Varghese N., Submissions S.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FMYI01000006; SDC31503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6KKL3; -.
DR   STRING; 1612202.SAMN05421734_106122; -.
DR   OrthoDB; 1641940at2; -.
DR   Proteomes; UP000242949; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF4; PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242949};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        30..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        276..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..404
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   420 AA;  45358 MW;  000172876889C8DF CRC64;
     MSNTGFQQKL QKVAGKISSN RYLKAVSDGL MSVVAVLIIG AFSTLLSEMA IEPYQNFITN
     IGIKGLLEIP AQYTTEMVAL YAVFFIAFKL AGSFEKEGSS AGLIALMSFL VLTPTTMLEE
     DPVLPFQFLG AQGLFVAIIV GLVSARLYVL IVNKGLTIKM PAGVPPTVSK TFIGLVPAII
     IVIFFTIISF LFTFTPFGNM HEFVYSFIQA PMQNLGGGFW SLIAFTLVVH GLWLLGIHGM
     LVVLPIYLSI WMPLGVENLD ALAAGEELPN IVNTGFAHVF MMLGGSGATL GLAIIMAFLA
     RSKRYKTLGK IALPGSFFGI NEPLLFGLPI VLNPYLAVPF VVAPLVSVTI PYFLMSTGII
     ARTAGAHLPL GTPTFFNAVV QGGVVLLIVQ IIMIIVTGLI YYPFFRVLDK QALEQEKSAE
//