ID   A0A1G6L778_9BURK        Unreviewed;       377 AA.
AC   A0A1G6L778;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Thiamine-phosphate diphosphorylase {ECO:0000313|EMBL:SDC39202.1};
GN   ORFNames=SAMN05216345_10299 {ECO:0000313|EMBL:SDC39202.1};
OS   Cupriavidus sp. YR651.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1855315 {ECO:0000313|EMBL:SDC39202.1, ECO:0000313|Proteomes:UP000198719};
RN   [1] {ECO:0000313|Proteomes:UP000198719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR651 {ECO:0000313|Proteomes:UP000198719};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004948}.
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DR   EMBL; FMYZ01000002; SDC39202.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6L778; -.
DR   STRING; 1855315.SAMN05216345_10299; -.
DR   OrthoDB; 9789949at2; -.
DR   Proteomes; UP000198719; Unassembled WGS sequence.
DR   GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00564; TMP_TenI; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR036206; ThiamineP_synth_sf.
DR   InterPro; IPR022998; ThiamineP_synth_TenI.
DR   PANTHER; PTHR20857:SF15; THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME; 1.
DR   PANTHER; PTHR20857; THIAMINE-PHOSPHATE PYROPHOSPHORYLASE; 1.
DR   Pfam; PF02581; TMP-TENI; 1.
DR   SUPFAM; SSF51391; Thiamin phosphate synthase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198719};
KW   Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977}.
FT   DOMAIN          180..358
FT                   /note="Thiamine phosphate synthase/TenI"
FT                   /evidence="ECO:0000259|Pfam:PF02581"
SQ   SEQUENCE   377 AA;  39575 MW;  23BEC8A9A1E0072D CRC64;
     MTRQGVAATV DAALFKDLMA RFGATFGRDK AEWRAWPLAN APAALGRHDV VLADGEAAAD
     AIDRIAAAGA VLIESDREGG RWIDTVRSPM GIWVLEVAAD DDTPHSAAFV AVLLAAMSLH
     FPAHDALCIA RAWQPGTSAW PSDFARFPRV RHAALASPDQ PAAPFAPCPP DLGLYAVMPS
     AAWIETLVPL AVPTVQLRFK SDDVEAVREE VARAATAAKG ASSRLFINDH WRVAIDYHAS
     CGGDSGIYGI HLGQEDLDEA DLDAIRASGL RLGVSTHGYA EMLRVAAIAP SYLALGAIFP
     TTTKVMPTSP QGMGRFQAYV ALMKPVIPSL VGIGGVNATN MPEVLAVGVG SAAVVRAITE
     AHDVPAAVAG LHALFGR
//