ID A0A1G6LWH2_9BACI Unreviewed; 403 AA.
AC A0A1G6LWH2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=HtrA-like peptidase. Serine peptidase. MEROPS family S01B {ECO:0000313|EMBL:SDC47613.1};
GN ORFNames=SAMN05421737_10926 {ECO:0000313|EMBL:SDC47613.1};
OS Shouchella lonarensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Shouchella.
OX NCBI_TaxID=1464122 {ECO:0000313|EMBL:SDC47613.1, ECO:0000313|Proteomes:UP000242662};
RN [1] {ECO:0000313|Proteomes:UP000242662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=25nlg {ECO:0000313|Proteomes:UP000242662};
RA Varghese N., Submissions S.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; FMYM01000009; SDC47613.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6LWH2; -.
DR STRING; 1464122.SAMN05421737_10926; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000242662; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000242662};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 287..388
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 403 AA; 42402 MW; 8F7CBDC77C1F749C CRC64;
MGYYDEHDER QTSRQRPVKR LSGLSAFGGA IIGGALVLIA SPVMSSLGLG MNDEKQSSQL
PETTIESGSG DVINVDIRSA VTEIVSKVSD AVVGVINLQE AGMFGSEASS EQGTGSGVIY
KKAGDNAFVV TNQHVIAGAS EVEVALTDGK RVPARVVGED QLMDLAVLEI EGKHVDTVAK
FGNSDDLQVG EPAIAIGNPL GLEFAGSVTQ GIISAKERSI PVDLNGNGQI DWNAEVLQTD
AAINPGNSGG PLINMNGEVI GINSMKIDGD AEGLGFAIPS AIVQPILADL EEHGEVRRPA
LGITLRALNE IPSSYWQETF KLPEDVTGGI VVIGVAPNSS ADKAGLKERD VIVEVEGEAV
QSGQELRKIL YAEKSIGDKV TLTFYREGKK ETVEATLIEQ QDV
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