ID A0A1G6M7A7_9BACT Unreviewed; 649 AA.
AC A0A1G6M7A7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN Name=feoB {ECO:0000313|EMBL:TGG87485.1};
GN ORFNames=E4650_06990 {ECO:0000313|EMBL:TGG87485.1}, SAMN04488588_1256
GN {ECO:0000313|EMBL:SDC51340.1};
OS Geotoga petraea.
OC Bacteria; Thermotogota; Thermotogae; Petrotogales; Petrotogaceae; Geotoga.
OX NCBI_TaxID=28234 {ECO:0000313|EMBL:SDC51340.1, ECO:0000313|Proteomes:UP000199322};
RN [1] {ECO:0000313|EMBL:SDC51340.1, ECO:0000313|Proteomes:UP000199322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WG14 {ECO:0000313|EMBL:SDC51340.1,
RC ECO:0000313|Proteomes:UP000199322};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TGG87485.1, ECO:0000313|Proteomes:UP000297288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HO-Geo1 {ECO:0000313|EMBL:TGG87485.1,
RC ECO:0000313|Proteomes:UP000297288};
RA Grouzdev D.S., Semenova E.M., Sokolova D.S., Tourova T.P., Poltaraus A.B.,
RA Nazina T.N.;
RT "Draft genome sequence data and analysis of a Fermenting Bacterium, Geotoga
RT petraea strain HO-Geo1, isolated from heavy-oil petroleum reservoir in
RT Russia.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU362098}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU362098}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC {ECO:0000256|RuleBase:RU362098}.
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DR EMBL; FMYV01000004; SDC51340.1; -; Genomic_DNA.
DR EMBL; SRME01000004; TGG87485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6M7A7; -.
DR STRING; 28234.SAMN04488588_1256; -.
DR OrthoDB; 9809127at2; -.
DR Proteomes; UP000199322; Unassembled WGS sequence.
DR Proteomes; UP000297288; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01879; FeoB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003373; Fe2_transport_prot-B.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR030389; G_FEOB_dom.
DR InterPro; IPR011642; Gate_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR NCBIfam; TIGR00437; feoB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43185:SF1; FE(2+) TRANSPORTER FEOB; 1.
DR PANTHER; PTHR43185; FERROUS IRON TRANSPORT PROTEIN B; 1.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF02421; FeoB_N; 1.
DR Pfam; PF07670; Gate; 2.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51711; G_FEOB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|PIRSR:PIRSR603373-
KW 1}; Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU362098};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496,
KW ECO:0000256|RuleBase:RU362098};
KW Magnesium {ECO:0000256|PIRSR:PIRSR603373-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR603373-2};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRSR:PIRSR603373-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199322};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362098};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362098};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 275..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 331..355
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 375..397
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 409..435
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 441..461
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 503..520
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 593..613
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT TRANSMEM 622..644
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362098"
FT DOMAIN 2..164
FT /note="FeoB-type G"
FT /evidence="ECO:0000259|PROSITE:PS51711"
FT BINDING 9..16
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-1"
FT BINDING 20
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-2"
FT BINDING 23
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-2"
FT BINDING 24
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-2"
FT BINDING 34..38
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-1"
FT BINDING 55..58
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-1"
FT BINDING 115..118
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR603373-1"
SQ SEQUENCE 649 AA; 72951 MW; 0CF9E1638EDE1438 CRC64;
MSKEVALIGN PNVGKTSIFN LLTGTRQYVA NWPGVTVERK VGISNINGEK YRIVDLPGIY
TLSANSEDEK VARDFFINEA PDTVLLIADA LNLERTFYLL LQLIEMNLPV VLAINSIDEA
EEKNKIVNTE VISKTLNIPV VLTSAKKNIG IDELKEKIEK LNLNDKEIYY DIEYPEKIKE
FIRKVEEIFE KDDNLKAFNK KWLALNIIEF GLDTNLISDD LKSEIGKNFD VEKLQELYIN
WKFEFITSIS ETAYLSKGID WSLRDMLDHV FTHKVLGIFI YILALFMVFS LTFTVSAPLS
DLLDMGFVAL AEIVGNTIEI DWLSSLLSDG IISGVGGVLV FIPQIFTLFF FMGFLEESGY
LPRAAFLVDK LVRKFGLSGR SFMSIILGFG CNVPAIMSTK AVSNKKERIA LILSIPFASC
SARLPVYILL ISAFFSTNAA TIMLLVYITS IFLVLISAKI IELFIKDKES IPFTIEMPRF
RMPTFRNLLL YTWNRGKHFL EKAGGIILVA SILVWALTYF PNTGQDITTS FAAMIGKFFE
PLTDHLGWDW RINTGLFFGV AAKEIVVSTY STLFTGGSSL VVSLRNALSP QSALALIFFV
LAYIPCFATL GVIKSETRSN KLIVFTLFYT TIVAYLLANL VYYVSGWIL
//
