ID A0A1G6P5N0_9BURK Unreviewed; 325 AA.
AC A0A1G6P5N0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Pyruvate dehydrogenase E1 component beta subunit {ECO:0000313|EMBL:SDC74715.1};
GN ORFNames=SAMN05216345_103542 {ECO:0000313|EMBL:SDC74715.1};
OS Cupriavidus sp. YR651.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1855315 {ECO:0000313|EMBL:SDC74715.1, ECO:0000313|Proteomes:UP000198719};
RN [1] {ECO:0000313|Proteomes:UP000198719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR651 {ECO:0000313|Proteomes:UP000198719};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; FMYZ01000003; SDC74715.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6P5N0; -.
DR STRING; 1855315.SAMN05216345_103542; -.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000198719; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:SDC74715.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198719}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 325 AA; 34219 MW; 5753E80B2B567D96 CRC64;
MAELHLVEAV NQALAHALAN DPDVVLLGED IGVNGGVFRA TVGLQARFGE ARVIDTPLAE
GGIVGAAIGM AAMGLKPVAE IQFAGFIHPA IDNILNHAGH MRHRTRGRLG CPMVVRAPSG
AGIHAPEHHS ESPEAMLAHI PGIRVVMPSS PARAYGLLLA AIRDPDPVIF LEPTRLYRLF
RQEVPDDGEA LPLDACFMLR DGADITLVSW GAMLQETLAA ADQLAEEGVA AAVIDVATLK
PLDMETIIES VAQTGRCVIV HEAPRTAGLG AEIAANLADA GLYSLSAPVQ RVTGFDTVVP
LARLEHCYLP SVARIVDAAR RALAT
//
