ID   A0A1G6SZ49_9BURK        Unreviewed;       340 AA.
AC   A0A1G6SZ49;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Isopenicillin N synthase {ECO:0000313|EMBL:SDD22033.1};
GN   ORFNames=SAMN05192589_10511 {ECO:0000313|EMBL:SDD22033.1};
OS   Paracidovorax valerianellae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Paracidovorax.
OX   NCBI_TaxID=187868 {ECO:0000313|EMBL:SDD22033.1, ECO:0000313|Proteomes:UP000198781};
RN   [1] {ECO:0000313|EMBL:SDD22033.1, ECO:0000313|Proteomes:UP000198781}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16619 {ECO:0000313|EMBL:SDD22033.1,
RC   ECO:0000313|Proteomes:UP000198781};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC       family. {ECO:0000256|RuleBase:RU003682}.
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DR   EMBL; FMZC01000005; SDD22033.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6SZ49; -.
DR   STRING; 187868.SAMN05192589_10511; -.
DR   OrthoDB; 21825at2; -.
DR   Proteomes; UP000198781; Unassembled WGS sequence.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR026992; DIOX_N.
DR   InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR   InterPro; IPR027443; IPNS-like_sf.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR47990:SF27; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR   Pfam; PF14226; DIOX_N; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   3: Inferred from homology;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Iron {ECO:0000256|RuleBase:RU003682};
KW   Metal-binding {ECO:0000256|RuleBase:RU003682};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198781}.
FT   DOMAIN          196..307
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
FT   REGION          112..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   340 AA;  38435 MW;  839125151128F6FB CRC64;
     MQSTTDHPTT ASHATTADVR AELEKEARMG GLGAETSTRE IRRIDLTDFE HRKEEIAEQL
     WSASVEIGFF QVTGHGIPVE DIRSAFARAE AFFDLPRETK AQWPLARNAG WEHKAQVRPS
     TRTPDQKESY QVTRPRMAGL WPTEAELPGF QEATLRFESQ CWHVGMQLLS CFAHKLGFAQ
     DFFTQAHDPS SAAYQSTLRM LHYFAVDPAL KDELGLWRAG AHTDFDCLTL LFQRPGQGGL
     QVLPGKEMES RQWTSVEPAE GVITCNIGDM LTRWSDDQLP SNFHRVRNPL PHEYQGARYS
     LAFFCQANED AAVEGPGRKY PAIQAGEYLR QRITANFAKY
//