ID   A0A1G6VJA0_9PROT        Unreviewed;       308 AA.
AC   A0A1G6VJA0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:SDD53604.1};
GN   ORFNames=SAMN04487779_100968 {ECO:0000313|EMBL:SDD53604.1};
OS   Belnapia rosea.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Belnapia.
OX   NCBI_TaxID=938405 {ECO:0000313|EMBL:SDD53604.1, ECO:0000313|Proteomes:UP000198925};
RN   [1] {ECO:0000313|EMBL:SDD53604.1, ECO:0000313|Proteomes:UP000198925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CPCC 100156 {ECO:0000313|EMBL:SDD53604.1,
RC   ECO:0000313|Proteomes:UP000198925};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR   EMBL; FMZX01000009; SDD53604.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G6VJA0; -.
DR   STRING; 938405.SAMN02927895_01407; -.
DR   OrthoDB; 9803287at2; -.
DR   Proteomes; UP000198925; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198925}.
FT   DOMAIN          8..182
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          186..248
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   SITE            139
FT                   /note="Important for catalytic activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000105-1"
SQ   SEQUENCE   308 AA;  32567 MW;  B2E6093671A9BC94 CRC64;
     MARPIRRIAV IGAGTIGASW AAWFLSRGLE VVASDPSPDA PGLIRRMVET AWPILQQLGA
     TADADPGRWR FEPDPVKAVE GCDAVQESAP ERYEVKQPLL RAISAALPEG ALILLSSSGL
     LVSRLSEGCT HPERVVIGHP FNPPHLIPLV EVVGGTTASP EAVQAAVAFY QAIGKYPIVL
     NKEVPGHLAN RLQAALWREA VHMVAEGVAS VADVDAAISQ GPGLRWALMG PHATFHLAGG
     EGGYAHFMHH LMPAVTSWWE SLGNPVLTPE LQKALIDGVT QETGGRPIPA LAADRDAALV
     RLLAAKTG
//