ID A0A1G6W8G3_9RHOB Unreviewed; 526 AA.
AC A0A1G6W8G3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=SAMN05421538_10250 {ECO:0000313|EMBL:SDD61345.1};
OS Paracoccus isoporae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=591205 {ECO:0000313|EMBL:SDD61345.1, ECO:0000313|Proteomes:UP000199344};
RN [1] {ECO:0000313|EMBL:SDD61345.1, ECO:0000313|Proteomes:UP000199344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22220 {ECO:0000313|EMBL:SDD61345.1,
RC ECO:0000313|Proteomes:UP000199344};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; FNAH01000002; SDD61345.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6W8G3; -.
DR STRING; 591205.SAMN05421538_10250; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000199344; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:SDD61345.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199344}.
FT DOMAIN 308..429
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 526 AA; 58609 MW; E8821B450ECE387B CRC64;
MREFAHLLER LAFTPQRNGK LRLLGRYFGA TPDPERGLAL AALTGDLKLR AVTSSMLRGL
ATARVDDQLF AASYDFVGDL AETIALIWPE PETPPNDPDL PLPMLVEELR STGKAGLPAL
IASRLDALNP SERYAYLKLA TGGLRVGVSA RLARAALAEY GELPLTEIEE IWHGLTPPYL
ELFQWAEGGE KPVSAALAPF RPVMLSTATD LDALQSLDPA DFAAEWKWDG IRVQAVSDQG
TRRLYSRTGE DIGGAFPDLL DRLDFDGVID GELLVRRGDL VGSFGDLQQR LNRKTVSKKL
LASHPAGLRA YDLLLWGGRD LRQMPFESRR ARLEAAIEGL DDRRIDASPL LPFDTWEDLA
ALRADPPDTV IEGIMLKRRD SAYLAGRIRG PWFKWKRDPM VIDAVLMYAQ RGHGKRSGYY
SDFTFGVWDG DELVPVGKAY FGFTDEELKD LDRFVRNNTV DRFGPVRAVA QKKVVEVAFE
GLNRSARHKS GVAMRFPRIS RIRDDKPAGE ADRIETLRDM LPPELA
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