ID A0A1G6X719_9MICO Unreviewed; 863 AA.
AC A0A1G6X719;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Polynucleotide 3'-phosphatase /polynucleotide 5'-hydroxyl-kinase /polynucleotide 2',3'-cyclic phosphate phosphodiesterase {ECO:0000313|EMBL:SDD73643.1};
GN ORFNames=SAMN05216410_0095 {ECO:0000313|EMBL:SDD73643.1};
OS Sanguibacter gelidistatuariae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Sanguibacteraceae;
OC Sanguibacter.
OX NCBI_TaxID=1814289 {ECO:0000313|EMBL:SDD73643.1, ECO:0000313|Proteomes:UP000199039};
RN [1] {ECO:0000313|EMBL:SDD73643.1, ECO:0000313|Proteomes:UP000199039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISLP-3 {ECO:0000313|EMBL:SDD73643.1,
RC ECO:0000313|Proteomes:UP000199039};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMYH01000010; SDD73643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G6X719; -.
DR STRING; 1814289.SAMN05216410_0095; -.
DR OrthoDB; 9807890at2; -.
DR Proteomes; UP000199039; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:SDD73643.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199039};
KW Transferase {ECO:0000313|EMBL:SDD73643.1}.
FT DOMAIN 182..378
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 477..858
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
SQ SEQUENCE 863 AA; 93871 MW; 7B6CFBDA703F1604 CRC64;
MTEISVPDLS LIVLVGASGS GKSTFAATHF GAFETVSSDF CRGLVSNDEN SQEATADAFD
LLAYIVGKRL DAGLLTVVDA TNVQPHARKS LAELARAHDV LPVAVVLDVG EDVCLTRNAA
RADRSLPAHV VRRQREQLRR SLRGLGREGF RDVHVLHSAE EVEATTIVRH PLRSDRRTEL
GPFDVIGDVH GCRSELESLL VTLGYTLVHD DAGRPVDAVP PEGRRAVFLG DLVDRGPDSP
GVLRLVMGIV AAGHALAVPG NHENKLVRAL DGRKVQVSHG LAETLAQLAE EPEEFRRDVR
AFCDGLVAHL VLDEGRLVVA HAGLKEAYHG RASGRVRSFA LYGETTGETD EFGLPVRYPW
AEDYRGRATV LYGHTPTPVA HWVNNTMCLD TGVVFGGHLS ALRYPEREVV QVPAERVWYE
PVKPFPVAGS EAGVAVAESG GNRTPDLLDV TDVLGKRVVE TRTHGRVGIA AENAAGALEV
MSRFALDPRW LLYLPPTMSP CATSSRDGLL EHPAEAFAQL RADGVDQAVC EEKHMGSRAV
VLVCRDQETA SSRFSIPEGM TGVVHTRTGR SFLDDARTEE LLRWLRSAAD AAGTWKTAGV
DGGESGWLLF DCELMPWSLK AEPLLREQYA SVGAAARSAL PAAVRTLETA ERAGLPVGDL
LARTRSRATN AEGFADAYRR YAWAVDGLDG VRLAPFQLLA AEGSTFHDRD HLWHLGVVDE
LVAADTSGLL QATRRLVVDL DDEGSVAAGT AWWEELTGAG GEGMVVKPVA NLVRGRRGLV
QPGIKVRGRE YLRIIYGPDY TEPEHLARLR ERGLGRKRSL ALREYALGIE ALERFRDDEP
LWRVHEAVFA VLALESEPVD PRL
//
