ID   A0A1G6XQ73_9NOCA        Unreviewed;       108 AA.
AC   A0A1G6XQ73;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Small multidrug resistance pump {ECO:0000313|EMBL:SDD80121.1};
GN   ORFNames=SAMN05444580_106300 {ECO:0000313|EMBL:SDD80121.1};
OS   Rhodococcus tukisamuensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=168276 {ECO:0000313|EMBL:SDD80121.1, ECO:0000313|Proteomes:UP000199417};
RN   [1] {ECO:0000313|EMBL:SDD80121.1, ECO:0000313|Proteomes:UP000199417}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 11308 {ECO:0000313|EMBL:SDD80121.1,
RC   ECO:0000313|Proteomes:UP000199417};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr
CC       subfamily. {ECO:0000256|ARBA:ARBA00007822}.
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DR   EMBL; FNAB01000006; SDD80121.1; -; Genomic_DNA.
DR   RefSeq; WP_072845029.1; NZ_FNAB01000006.1.
DR   AlphaFoldDB; A0A1G6XQ73; -.
DR   STRING; 168276.SAMN05444580_106300; -.
DR   Proteomes; UP000199417; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561:SF1; MULTIDRUG TRANSPORTER EMRE; 1.
DR   PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199417};
KW   Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   108 AA;  11259 MW;  EE6B0617D4824B0D CRC64;
     MTWVLLMAAI VLEVTATLSL KASDGFTRRR WIAPVVLGYL ASFGLIAVVL ARGMAVGVVY
     GIWVACGVAL TAVLGRVVFG EPLTRAMRFG IALIIGGVLL IELGSVAG
//